Evidence map›Paper›PMID 33622106›Full record

ArticleOpen biology2021

A visual atlas of meiotic protein dynamics in living fission yeast.

Wilber Escorcia, Vishnu P Tripathi, Ji-Ping Yuan, Susan L Forsburg

Abstract read
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wilber EscorciaMolecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA.
Vishnu P TripathiMolecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA.
Ji-Ping YuanMolecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA.
Susan L ForsburgMolecular and Computational Biology Program, University of Southern California, Los Angeles, CA 90089, USA.

Funding

Mechanisms linking replication stress to genome instability in fission yeastR35GM118109 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2016 to 2025
$7.1M
USC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3M
NIA NIH HHS T32 AG052374NIGMS NIH HHS R35 GM118109
6 · The paper itself

Abstract

Meiosis is a carefully choreographed dynamic process that re-purposes proteins from somatic/vegetative cell division, as well as meiosis-specific factors, to carry out the differentiation and recombination pathway common to sexually reproducing eukaryotes. Studies of individual proteins from a variety of different experimental protocols can make it difficult to compare details between them. Using a consistent protocol in otherwise wild-type fission yeast cells, this report provides an atlas of dynamic protein behaviour of representative proteins at different stages during normal zygotic meiosis in fission yeast. This establishes common landmarks to facilitate comparison of different proteins and shows that initiation of S phase likely occurs prior to nuclear fusion/karyogamy.

Indexed as

MeiosisGene Expression Regulation, FungalSchizosaccharomycesSchizosaccharomyces pombe ProteinsSchizosaccharomyces pombe ProteinscohesinhistonemeiosismicrotubulePCNAspindle assembly checkpoints

Identifiers

PMID33622106
PMCPMC8061692

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.