Evidence map›Paper›PMID 33622085›Full record

ArticleJournal of dental research2021

Aberrant Brain Signal Variability and COMT Genotype in Chronic TMD Patients.

M Lim, T D Nascimento, D J Kim, V L Ellingrod, A F DaSilva

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. High-definition tDCS over primary motor cortex modulates brain signal variability and functional connectivity in episodic migraine.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Trial
  2. Functional Magnetic Resonance Imaging Signal Variability Is Associated With Neuromodulation in Fibromyalgia.Neuromodulation : journal of the International Neuromodulation Society · 2023
    Trial
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M LimHeadache and Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
T D NascimentoHeadache and Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
D J KimHeadache and Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
V L EllingrodCollege of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
A F DaSilvaHeadache and Orofacial Pain Effort (H.O.P.E.), Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · US

Funding

Investigation and Modulation of the Mu-Opioid Mechanism in Chronic TMD (in vivo)U01DE025633 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DASILVA, ALEXANDRE · 2016 to 2020
$2.4M
Structural and Molecular Neuroplasticity in Chronic Trigeminal PainK23NS062946 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DASILVA, ALEXANDRE · 2009 to 2013
$779k
Brain as a Research and Therapeutic Target in Chronic TMDR56DE022637 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DASILVA, ALEXANDRE · 2013 to 2014
$773k
NIDCR NIH HHS R56 DE022637NIDCR NIH HHS U01 DE025633NINDS NIH HHS K23 NS062946
6 · The paper itself

Abstract

The analysis of brain signal variability is a promising approach to understand pathological brain function related to chronic pain. This study investigates whether blood-oxygen-level-dependent signal variability (BOLD

Indexed as

Catechol O-MethyltransferaseTemporomandibular Joint DisordersBrainGenotypeHumansMagnetic Resonance ImagingCatechol O-MethyltransferaseCOMT protein, humanchronic painfacial painfMRIgeneticsneuroimagingtemporomandibular disorders

Identifiers

PMID33622085
PMCPMC8221705
OpenAlexW3132930939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.