ArticleNeuroImage2021
The neurocognitive correlates of brain entropy estimated by resting state fMRI.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Lifespan trajectories of the brain's functional complexity characterized by multiscale sample entropy.NeuroImage · 2026Article
- Resting-State Brain Entropy Reveals Altered Neural Dynamics and Cognitive Associations in Mild Traumatic Brain Injury: A Longitudinal Study.Journal of neuroscience research · 2026Article
- Baseline electrophysiology versus oxidative metabolism as traits of inter-network differences in neurometabolic association.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- Poorer Physical Function Is Associated With Elevated Spatial Entropy in the Aging Brain Network Landscape.Aging cell · 2026Article
- Reduced but Reversible Brain Entropy After Occupational Partial Sleep Deprivation in Night-Shift Medical Staff.Brain and behavior · 2026Article
- BOLD complexity characterizes glioblastoma survival via voxel-wise and localized sample entropy.Journal of neuro-oncology · 2026Article
- Brain entropy as a biomarker of major depression in adolescents and young adults: insights from multimodal resting-state functional magentic resonance imaging.Psychoradiology · 2026Article
- Consistent Brain Entropy Changes During Rumination Across Three Magnetic Resonance Imaging Scanners.Neural plasticity · 2026Article
- Reduced brain entropy in migraine with partial restoration during attacks: A resting-state fMRI study.medRxiv : the preprint server for health sciences · 2025Article
- Brain Entropy: Linking Brain Structure to Task Activation.bioRxiv : the preprint server for biology · 2025Article
- Resting-State Functional MRI Analyses for Brain Activity Characterization: A Narrative Review of Features and Methods.The European journal of neuroscience · 2025Review
- The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia.Alzheimer's research & therapy · 2025Article
- Chronic pain is associated with greater brain entropy in the prefrontal cortex.The journal of pain · 2025Article
- Normative Brain Entropy Across the Lifespan.bioRxiv : the preprint server for biology · 2025Article
- Article
- The effects of intermittent theta burst stimulation (iTBS) on resting-state brain entropy (BEN).Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Complexity of intrinsic brain activity in relapsing-remitting multiple sclerosis patients: patterns, association with structural damage, and clinical disability.La Radiologia medica · 2025Observational
- The different impacts of functional network centrality and connectivity on the complexity of brain signals in healthy control and first-episode drug-naïve patients with major depressive disorder.Brain imaging and behavior · 2025Article
- rsfMRI-based brain entropy is negatively correlated with gray matter volume and surface area.Brain structure & function · 2025Article
- Resting state fMRI-based temporal coherence mapping.Imaging neuroscience (Cambridge, Mass.) · 2025Article
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Abstract
Resting state brain activity consumes most of brain energy, likely creating and maintaining a reserve of general brain functionality. The latent reserve if it exists may be reflected by the profound long-range fluctuations of resting brain activity. The long-range temporal coherence (LRTC) can be characterized by resting state fMRI (rsfMRI)-based brain entropy (BEN) mapping. While BEN mapping results have shown sensitivity to neuromodulations or disease conditions, the underlying neuromechanisms especially the associations of BEN or LRTC to neurocognition still remain unclear. To address this standing question and to test a novel hypothesis that resting BEN reflects a latent functional reserve through the link to general functionality, we mapped resting BEN of 862 young adults and comprehensively examined its associations to neurocognitions using data from the Human Connectome Project (HCP). Our results unanimously highlighted two brain circuits: the default mode network (DMN) and executive control network (ECN) through their negative associations of BEN to general functionality, which is independent of age and sex. While BEN in DMN/ECN increases with age, it decreases with education years. These results demonstrated the neurocognitive correlates of resting BEN in DMN/ECN and suggest resting BEN in DMN/ECN as a potential proxy of the latent functional reserve that facilitates general brain functionality and may be enhanced by education.
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