ArticleNeuroImage2021
Variable flip angle echo planar time-resolved imaging (vFA-EPTI) for fast high-resolution gradient echo myelin water imaging.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Effect of basis choice on quantitative parameter estimation in accelerated subspace reconstructions.Magnetic resonance letters · 2026Article
- Water/Fat Separated Echo Planar Time-Resolved Imaging (WFS-EPTI) for Distortion-Free Multi-Contrast MRI.Magnetic resonance in medicine · 2026Article
- Myelin water imaging from accelerated 3D-GRASE acquisitions using subspace constrained reconstruction.Magma (New York, N.Y.) · 2025Article
- Time-resolved MR fingerprinting for TMagnetic resonance in medicine · 2025Article
- Romer-EPTI: Rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale diffusion MRI and microstructure imaging.Magnetic resonance in medicine · 2025Article
- Microstructure-Informed Myelin Mapping (MIMM) from routine multi-echo gradient echo data using multiscale physics modeling of iron and myelin effects and QSM.Magnetic resonance in medicine · 2025Article
- Single-shot echo planar time-resolved imaging for multi-echo functional MRI and distortion-free diffusion imaging.Magnetic resonance in medicine · 2025Article
- Spherical echo-planar time-resolved imaging (sEPTI) for rapid 3D quantitativeMagnetic resonance in medicine · 2025Article
- High-resolution myelin-water fraction and quantitative relaxation mapping using 3D ViSTa-MR fingerprinting.Magnetic resonance in medicine · 2024Article
- Romer-EPTI: rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale dMRI and microstructure imaging.bioRxiv : the preprint server for biology · 2024Article
- High-resolution myelin-water fraction and quantitative relaxation mapping using 3D ViSTa-MR fingerprinting.ArXiv · 2023Article
- Motion-corrected 3D-EPTI with efficient 4D navigator acquisition for fast and robust whole-brain quantitative imaging.Magnetic resonance in medicine · 2022Article
- Empirical transmit field bias correction of T1w/T2w myelin maps.NeuroImage · 2022Article
- 3D Echo Planar Time-resolved Imaging (3D-EPTI) for ultrafast multi-parametric quantitative MRI.NeuroImage · 2022Article
- Distortion-Free Diffusion Imaging Using Self-Navigated Cartesian Echo-Planar Time Resolved Acquisition and Joint Magnitude and Phase Constrained Reconstruction.IEEE transactions on medical imaging · 2022Article
- Simultaneous pure TNeuroImage · 2021Article
- Lesion probability mapping in MS patients using a regression network on MR fingerprinting.BMC medical imaging · 2021Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Myelin water imaging techniques based on multi-compartment relaxometry have been developed as an important tool to measure myelin concentration in vivo, but are limited by the long scan time of multi-contrast multi-echo acquisition. In this work, a fast imaging technique, termed variable flip angle Echo Planar Time-Resolved Imaging (vFA-EPTI), is developed to acquire multi-echo and multi-flip-angle gradient-echo data with significantly reduced acquisition time, providing rich information for multi-compartment analysis of gradient-echo myelin water imaging (GRE-MWI). The proposed vFA-EPTI method achieved 26 folds acceleration with good accuracy by utilizing an efficient continuous readout, optimized spatiotemporal encoding across echoes and flip angles, as well as a joint subspace reconstruction. An approach to estimate off-resonance field changes between different flip-angle acquisitions was also developed to ensure high-quality joint reconstruction across flip angles. The accuracy of myelin water fraction (MWF) estimate under high acceleration was first validated by a retrospective undersampling experiment using a lengthy fully-sampled data as reference. Prospective experiments were then performed where whole-brain MWF and multi-compartment quantitative maps were obtained in 5 min at 1.5 mm isotropic resolution and 24 min at 1 mm isotropic resolution at 3T. Additionally, ultra-high resolution data at 600 µm isotropic resolution were acquired at 7T, which show detailed structures within the cortex such as the line of Gennari, demonstrating the ability of the proposed method for submillimeter GRE-MWI that can be used to study cortical myeloarchitecture in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.