Evidence map›Paper›PMID 33621481›Full record

ArticleCurrent biology : CB2021

Stem cell niche organization in the Drosophila ovary requires the ECM component Perlecan.

Alfonsa Díaz-Torres, Alicia E Rosales-Nieves, John R Pearson, Carmen Santa-Cruz Mateos, Miriam Marín-Menguiano, Owen J Marshall, Andrea H Brand, Acaimo González-Reyes

Open access · hybridAbstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  5. TheeLife · 2025
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  8. ThebioRxiv : the preprint server for biology · 2024
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  19. A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy.Matrix biology : journal of the International Society for Matrix Biology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alfonsa Díaz-TorresCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain.
Alicia E Rosales-NievesCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain.
John R PearsonCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain.
Carmen Santa-Cruz MateosCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain.
Miriam Marín-MenguianoCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain.
Owen J MarshallThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 1QN, UK; Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, TAS 7000, Australia.
Andrea H BrandThe Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 1QN, UK.
Acaimo González-ReyesCentro Andaluz de Biología del Desarrollo, CSIC/Universidad Pablo de Olavide/JA, Carretera de Utrera km 1, 41013 Sevilla, Spain. Electronic address: agonrey@upo.es.
Centro Andaluz de Biología del Desarrollo · ESUniversity of Cambridge · GBUniversity of Tasmania · AU

Funding

Cancer Research UK C6946/A14492Wellcome Trust
6 · The paper itself

Abstract

Stem cells reside in specialized microenvironments or niches that balance stem cell proliferation and differentiation.

Indexed as

DrosophilaStem Cell NicheAnimalsDrosophila melanogasterDrosophila ProteinsFemaleHeparan Sulfate ProteoglycansLigandsOvaryDrosophila ProteinsHeparan Sulfate ProteoglycansLigandsperlecanadult stem cellsDrosophila oogenesisECMgermline stem cellsovarian nichePerlecan

Identifiers

PMID33621481
PMCPMC8405445
OpenAlexW3132917353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.