Evidence map›Paper›PMID 33620616›Full record

ArticleAnnals of surgical oncology2021

Outcomes Following Percutaneous Microwave and Cryoablation of Lung Metastases from Adenoid Cystic Carcinoma of the Head and Neck: A Bi-Institutional Retrospective Cohort Study.

Konstantin S Leppelmann, Vincent M Levesque, Alexander C Bunck, Alexis M Cahalane, Michael Lanuti, Stuart G Silverman, Paul B Shyn, Florian J Fintelmann

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Konstantin S LeppelmannDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Vincent M LevesqueDepartment of Radiology, Brigham and Women's Hospital, Boston, MA, USA.
Alexander C BunckDepartment of Diagnostic and Interventional Radiology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Alexis M CahalaneDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Michael LanutiDepartment of Surgery, Massachusetts General Hospital, Boston, MA, USA.
Stuart G SilvermanDepartment of Radiology, Brigham and Women's Hospital, Boston, MA, USA.
Paul B Shyn *Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA.
Florian J Fintelmann *Department of Radiology, Massachusetts General Hospital, Boston, MA, USA. fintelmann@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-0119-3903
Brigham and Women's Hospital · USHarvard University · USUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

obectiveThe aim of this study was to report outcomes following percutaneous microwave and cryoablation of lung metastases from adenoid cystic carcinoma (ACC) of the head and neck. MATERIAL AND

methodsThis bi-institutional retrospective cohort study included 10 patients (6 females, median age 59 years [range 28-81]) who underwent 32 percutaneous ablation sessions (21 cryoablation, 11 microwave) of 60 lung metastases (median 3.5 tumors per patient [range 1-16]) from 2007 to 2019. Median tumor diameter was 16 mm [range 7-40], significantly larger for cryoablation (22 mm, p = 0.002). A median of two tumors were treated per session [range 1-7]. Technical success, local control, complications, and overall survival were assessed.

resultsPrimary technical success was achieved for 55/60 tumors (91.7%). Median follow-up was 40.6 months (clinical) and 32.5 months (imaging, per tumor). Local control at 1, 2, and 3 years was 94.7%, 80.8%, and 76.4%, respectively, and did not differ between ablation modalities. Five of fifteen recurrent tumors underwent repeat ablation, and secondary technical success was achieved in four (80%). Assisted local tumor control at 1, 2, and 3 years was 96.2%, 89.8%, and 84.9%, respectively. Complications occurred following 24/32 sessions (75.0%) and 57.2% Common Terminology Criteria for Adverse Events (CTCAE) lower than grade 3. Of 13 pneumothoraces, 7 required chest tube placements. Hemoptysis occurred after 7/21 cryoablation sessions, and bronchopleural fistula developed more frequently with microwave (p = 0.037). Median length of hospital stay was 1 day [range 0-10], and median overall survival was 81.5 months (IQR 40.4-93.1).

conclusionPercutaneous computed tomography-guided microwave and cryoablation can treat lung metastases from ACC of the head and neck. Complications are common but manageable, with full recovery expected.

Indexed as

Carcinoma, Adenoid CysticCryosurgeryKidney NeoplasmsLung NeoplasmsAdultAgedAged, 80 and overFemaleHumansMicrowavesMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesTreatment OutcomeAdenoid cystic carcinomaComputed tomography guidanceCryoablationLung metastasisMicrowave ablationPercutaneous ablation

Identifiers

PMID33620616
OpenAlexW3129711208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.