Evidence map›Paper›PMID 33620613›Full record

ArticleHistory and philosophy of the life sciences2021

Aging biomarkers and the measurement of health and risk.

Sara Green, Line Hillersdal

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in History and philosophy of the life sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Evolution of joint power across the lifespan during walking.Journal of neuroengineering and rehabilitation · 2025
    Article
  3. Revealing the Spatial Pattern of Brain Hemodynamic Sensitivity to Healthy Aging through Sparse Dynamic Causal Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Medawar and Hamilton on the selective forces in the evolution of ageing.History and philosophy of the life sciences · 2021
    Article
  13. Rethinking ageing: introduction.History and philosophy of the life sciences · 2021
    Article
  14. Article
  15. The plasticity of ageing and the rediscovery of ground-state prevention.History and philosophy of the life sciences · 2021
    Article
  16. What's my age again? Age categories as interactive kinds.History and philosophy of the life sciences · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sara GreenSection for History and Philosophy of Science, Department of Science Education, University of Copenhagen, Copenhagen, Denmark. sara.green@ind.ku.dk.ORCID http://orcid.org/0000-0001-7011-7202
Line HillersdalCentre for Medical Science and Technology Studies, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

Carlsbergfondet CF17-0016
6 · The paper itself

Abstract

Prevention of age-related disorders is increasingly in focus of health policies, and it is hoped that early intervention on processes of deterioration can promote healthier and longer lives. New opportunities to slow down the aging process are emerging with new fields such as personalized nutrition. Data-intensive research has the potential to improve the precision of existing risk factors, e.g., to replace coarse-grained markers such as blood cholesterol with more detailed multivariate biomarkers. In this paper, we follow an attempt to develop a new aging biomarker. The vision among the project consortium, comprising both research and industrial partners, is that the new biomarker will be predictive of a range of age-related conditions, which may be preventable through personalized nutrition. We combine philosophical analysis and ethnographic fieldwork to explore the possibilities and challenges of managing aging through bodily signs that are not straightforwardly linked to symptomatic disease. We document how the improvement of measurement brings about new conceptual challenges of demarcating healthy and unhealthy states. Moreover, we highlight that the reframing of aging as risk has social and ethical implications, as it is generative of normative notions of what constitutes successful aging and good citizenship.

Indexed as

AgingAnthropology, CulturalHealthRiskBiomarkersEthicsHumansBiomarkersAging biomarkerHealthy agingMedicalizationPersonalized nutritionPhilosophy of aging

Identifiers

PMID33620613
PMCPMC7901506
OpenAlexW3131282166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.