Evidence map›Paper›PMID 33620424›Full record

SynthesisEuropean heart journal. Acute cardiovascular care2021

The value of urinary sodium assessment in acute heart failure.

Gregorio Tersalvi, Jeroen Dauw, Alessio Gasperetti, Dario Winterton, Giacomo Maria Cioffi, Francesca Scopigni, Giovanni Pedrazzini, Wilfried Mullens

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European heart journal. Acute cardiovascular care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07464249 (Comparison of the Effectiveness of Bolus and Infusion Diuretic Therapy in the Management of Acute Heart Failure in Emergency Departments), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07464249 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparison of the Effectiveness of Bolus and Infusion Diuretic Therapy in the Management of Acute Heart Failure in Emergency Departments: a Randomised, Double-blind Clinical Study

TypeinterventionalSponsorSultan Abdulhamid Han Training and Research Hospital, Istanbul, TurkeyRan2024 to 2024Enrolled50ConditionsAcute Decompensated Heart Failure (ADHF)ArmsFurosemide Bolus, Furosemide Continuous İnfusion
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Gregorio TersalviDepartment of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland.
Jeroen DauwDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.
Alessio GasperettiCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Dario WintertonDepartment of Anesthesia and Intensive Care Medicine, ASST Monza, Monza, Italy.
Giacomo Maria CioffiDepartment of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland.
Francesca ScopigniDepartment of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland.
Giovanni PedrazziniDepartment of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland.
Wilfried MullensDepartment of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.
Epatocentro Ticino · CHZiekenhuis Oost-Limburg · BEASST Melegnano e della Martesana · ITCentro Cardiologico Monzino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute heart failure (AHF) is a frequent medical condition that needs immediate evaluation and appropriate treatment. Patients with signs and symptoms of volume overload mostly require intravenous loop diuretics in the first hours of hospitalization. Some patients may develop diuretic resistance, resulting in insufficient and delayed decongestion, with increased mortality and morbidity. Urinary sodium measurement at baseline and/or during treatment has been proposed as a useful parameter to tailor diuretic therapy in these patients. This systematic review discusses the current sum of evidence regarding urinary sodium assessment to evaluate diuretic efficacy in AHF. We searched Medline, Embase, and Cochrane Clinical Trials Register for published studies that tested urinary sodium assessment in patients with AHF.

Indexed as

Heart FailureSodium Potassium Chloride Symporter InhibitorsAcute DiseaseDiureticsHospitalizationHumansSodiumDiureticsSodiumSodium Potassium Chloride Symporter InhibitorsAcute heart failureDiureticNatriuresisUrinary sodiumVolume overload

Identifiers

PMID33620424
PMCPMC8294841
OpenAlexW3124688668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.