Evidence map›Paper›PMID 33620375›Full record

Observational studyInvestigative ophthalmology & visual science2021

Posture-Related Changes of Intraocular Pressure in Patients With Acute Primary Angle Closure.

Yun Hsia, Chien-Chia Su, Tsing-Hong Wang, Jehn-Yu Huang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Investigative ophthalmology & visual science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Predictors of visual field progression in acute and primary angle-closure disease: role of posture-related IOP changes and anterior segment structure.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Postural IOP elevation in Face-Down position in vitrectomized eyes: A Time-Related glaucoma risk indicator.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yun HsiaDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Chien-Chia SuDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Tsing-Hong WangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Jehn-Yu HuangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the posture-related change in intraocular pressure (IOP) of eyes with angle-closure disease and the associated factors. Methods: Eyes were prospectively enrolled and divided into three groups: eyes with acute primary angle-closure (APAC), fellow eyes of acute primary angle-closure (FAPAC), and eyes with nonacute primary angle-closure disease (PACD). All of them had been treated with laser peripheral iridotomy. IOP was measured in the sitting, supine, and lateral decubitus positions (LDP) five minutes after posture change. Anterior chamber angle parameters and angle-closure mechanism were evaluated by anterior segment optical coherence tomography. Results: Forty-four eyes were enrolled into each group. APAC eyes showed more LDP-Sitting IOP increase than fellow eyes (5.7 ± 2.7 vs. 2.2 ± 1.4 mm Hg, P < 0.001) and nonacute PACD eyes (3.6 ± 2.0 mm Hg, P < 0.001). LDP-sitting IOP change was higher in eyes with exaggerated lens vault (having shallow anterior chamber and volcano-like iris-lens configuration) than in those without it (APAC: 6.3 ± 2.6 vs. 3.9 ± 2.1 mm Hg, P = 0.011). Linear regression revealed that LDP-sitting IOP change in the APAC group was negatively associated with angle opening distance (AOD), trabecular iris space area, scleral spur angle, and anterior chamber depth (ACD1000). With multivariable stepwise regression analysis, AOD750 remained statistically significant (beta-coefficient = -8.36, P = 0.014). Conclusions: APAC eyes had significant posture-related IOP changes, associated with narrower angle structures and exaggerated lens vault.

Indexed as

Acute DiseaseAgedFemaleFollow-Up StudiesGlaucoma, Angle-ClosureGonioscopyHumansIntraocular PressureMalePostureProspective StudiesTomography, Optical Coherence

Identifiers

PMID33620375
PMCPMC7910642
OpenAlexW3131619616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.