Evidence map›Paper›PMID 33620316›Full record

ArticleeLife2021

Deficient spermiogenesis in mice lacking

Feng Wang, Maria Gracia Gervasi, Ana Bošković, Fengyun Sun, Vera D Rinaldi, Jun Yu, Mary C Wallingford, Darya A Tourzani, Jesse Mager, Lihua Julie Zhu and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome.The Journal of clinical endocrinology and metabolism · 2025
    Observational
  2. Article
  3. Review
  4. Review
  5. Article
  6. Knockout ofAnimals : an open access journal from MDPI · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Feng WangDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, United States.
Maria Gracia GervasiDepartment of Veterinary & Animal Sciences, University of Massachusetts Amherst, Amherst, United States.ORCID 0000-0002-5468-2700
Ana BoškovićDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, United States.
Fengyun SunDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, United States.
Vera D RinaldiDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0002-0051-1754
Jun YuDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, United States.
Mary C WallingfordDepartment of Veterinary & Animal Sciences, University of Massachusetts Amherst, Amherst, United States.
Darya A TourzaniDepartment of Veterinary & Animal Sciences, University of Massachusetts Amherst, Amherst, United States.
Jesse MagerDepartment of Veterinary & Animal Sciences, University of Massachusetts Amherst, Amherst, United States.
Lihua Julie ZhuDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, United States.
Oliver J RandoDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0003-1516-9397
Pablo E ViscontiDepartment of Veterinary & Animal Sciences, University of Massachusetts Amherst, Amherst, United States.
Lara StrittmatterElectron Microscopy Core, University of Massachusetts Medical School, Worcester, United States.
Ingolf BachDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0003-4505-8946
University of Massachusetts Chan Medical School · USUniversity of Massachusetts Amherst · US

Funding

PILOT AND FEASIBILITY PROGRAMP30DK032520 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CZECH, MICHAEL P · 1986 to 2010
$14.6M
Sperm Ca2+ Signaling and Energy Pathways in basic science and ARTR01HD038082 · NICHD · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI VISCONTI, PABLO E. · 2000 to 2025
$6.5M
Streamline assessment of early lethal phenotypes in the mouseR01HD083311 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MAGER, JESSE · 2015 to 2024
$6.5M
Dietary effects on the sperm epigenomeR01HD080224 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RANDO, OLIVER J · 2014 to 2022
$5.9M
tRNA fragments as transgenerational information carriersDP1ES025458 · NIEHS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RANDO, OLIVER J · 2014 to 2018
$4.2M
Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
Epigenetic regulation of X chromosomes during female mouse embryogenesisR01GM128168 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BACH, INGOLF M · 2018 to 2021
$1.5M
NICHD NIH HHS R01 HD038082NICHD NIH HHS R01 HD080224NICHD NIH HHS R01 HD083311NIDDK NIH HHS P30 DK032520NIEHS NIH HHS DP1 ES025458NIGMS NIH HHS R01 GM128168NIGMS NIH HHS T32 GM135096
6 · The paper itself

Abstract

The X-linked gene

Indexed as

AnimalsGenes, X-LinkedMaleMiceMice, KnockoutSertoli CellsSpermatogenesisUbiquitin-Protein LigasesRlim protein, mouseUbiquitin-Protein Ligasescytoplasmic reductiondevelopmental biologymousemouse geneticsRlimspermiogenesis

Identifiers

PMID33620316
PMCPMC7935487
OpenAlexW3129209424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.