Evidence map›Paper›PMID 33620096›Full record

ArticleJournal of medical virology2021

Estimation of undetected symptomatic and asymptomatic cases of COVID-19 infection and prediction of its spread in the USA.

Ashutosh Mahajan, Ravi Solanki, Namitha Sivadas

Abstract read
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. De novo design of anti-variant COVID-19 vaccine.Biology methods & protocols · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Estimation of Undetected Asymptomatic COVID-19 Cases in South Korea Using a Probabilistic Model.International journal of environmental research and public health · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ashutosh MahajanCentre for Nanotechnology Research, Vellore Institute of Technology, Vellore, India.ORCID http://orcid.org/0000-0002-1121-7542
Ravi SolankiVisvesvaraya National Institute of Technology, Nagpur, India.ORCID https://orcid.org/0000-0002-2105-0264
Namitha SivadasSchool of Electronics Engineering, Vellore Institute of Technology, Vellore, India.ORCID https://orcid.org/0000-0003-2504-7553

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reported COVID-19 cases in the United States of America have crossed over 10 million and a large number of infected cases are undetected whose estimation can be done if country-wide antibody testing is performed. In this study, we estimate this undetected fraction of the population by a modeling and simulation approach. We employ an epidemic model SIPHERD in which three categories of infection carriers, symptomatic, purely asymptomatic, and exposed are considered with different transmission rates that are taken dependent on the social distancing conditions, and the detection rate of the infected carriers is taken dependent on the tests done per day. The model is first validated for Germany and South Korea and then applied for prediction of the total number of confirmed, active and dead, and daily new positive cases in the United States. Our study predicts the possible outcomes of the infection if social distancing conditions are relaxed or kept stringent. We estimate that around 30.1 million people are already infected, and in the absence of any vaccine, 66.2 million (range: 64.3-68.0) people, or 20% (range: 19.4-20.5) of the population will be infected by mid-February 21 if social distancing conditions are not made stringent. We find the infection-to-fatality ratio to be 0.65% (range: 0.63-0.67).

Indexed as

SARS-CoV-2Computer SimulationCOVID-19HumansUnited Statescomputer modelingCoronavirusepidemiologypandemics

Identifiers

PMID33620096
PMCPMC8013178

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.