Evidence map›Paper›PMID 33619914›Full record

ArticleUnited European gastroenterology journal2021

European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations.

Stephan Miehlke, Danila Guagnozzi, Yamile Zabana, Gian E Tontini, Anne-Marie Kanstrup Fiehn, Signe Wildt, Johan Bohr, Ole Bonderup, Gerd Bouma, Mauro D'Amato and 22 more

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 108 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 6 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06031064 unknown statusnot on this mapstarted 2022, after this paper: background citation

External Validation of a Clinical Scoring System to Predict Microscopic Colitis in Patients With Chronic Watery Diarrhoea

TypeobservationalSponsorHospital Mutua de TerrassaRan2022 to 2024Enrolled200ConditionsMicroscopic Colitis
NCT06172647 unknown statusnot on this mapstarted 2022, after this paper: background citation

Intestinal Microbiome Adherent to the Mucosa in Microscopic Colitis in Comparison With Patients With Advanced Colon Adenomas

TypeobservationalSponsorHospital Mutua de TerrassaRan2022 to 2025Enrolled60ConditionsMicroscopic Colitis, Colorectal Cancer, Colon AdenomaArmsColonoscopy
3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 6 syntheses or guidelines pooled it, 206 citations in OpenAlex.

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  5. Microbiome Composition in Microscopic Colitis: A Systematic Review.International journal of molecular sciences · 2023
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 17 countries.

Stephan MiehlkeCenter for Digestive Diseases, Internal Medicine Center Eppendorf, Hamburg, Germany.
Danila GuagnozziNeuro-Immuno-Gastroenterology Group, Digestive Physiology and Pathophysiology Unit, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Yamile ZabanaCentro de Investigación Biomedica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.
Gian E TontiniDepartment of Pathophysiology and Organ Transplantation, University of Milan and Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Anne-Marie Kanstrup FiehnDepartment of Pathology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Signe WildtDepartment of Gastroenterology, Zealand University Hospital, Koege, Denmark.
Johan BohrDepartment of Medicine, Örebro University Hospital, Örebro University, Örebro, Sweden.
Ole BonderupDiagnostik Center, Hospitalenhed Midt, Regionshospitalet Silkeborg, Silkeborg, Denmark.
Gerd BoumaDepartment of Gastroenterology and Hepatology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Mauro D'AmatoSchool of Biological Sciences, Monash University, Clayton, Australia.
Peter J Heiberg EngelDepartment of Pathology, Zealand University Hospital, Roskilde, Denmark.
Fernando Fernandez-BanaresCentro de Investigación Biomedica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain.
Gilles MacaigneHepatogastroenterology Unit, Centre Hospitalier de Marne-la-Vallee, Jossigny, France.
Henrik HjortswangDepartment of Gastroenterology and Hepatology in Linköping, Linköping University, Linköping, Sweden.
Elisabeth Hultgren-HörnquistSchool of Medical Sciences, Örebro University, Örebro, Sweden.
Anastasios KoulaouzidisThe Royal Infirmary of Edinburgh, Endoscopy Unit, Edinburgh, UK.
Jouzas KupcinskasDepartment of Gastroenterology and Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Stefania LandolfiDepartment of Pathology, Hospital Universitari Vall d'Hebron, CIBERONC, Barcelona, Spain.ORCID https://orcid.org/0000-0002-1059-635X
Giovanni LatellaDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Alfredo LucendoDepartment of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Spain.ORCID https://orcid.org/0000-0003-1183-1072
Ivan LyutakovDepartment of Gastroenterology, Medical University of Sofia, University Hospital Tsaritsa Yoanna-ISUL, Sofia, Bulgaria.ORCID https://orcid.org/0000-0001-8883-1121
Ahmed MadischDepartment of Gastroenterology, CRH Clinic Siloah, Hannover, Germany.
Fernando MagroDepartment of Pharmacology, Hospital de Sao Joao, Porto, Portugal.
Wojciech MarliczDepartment of Gastroenterology, Pomeranian Medical University, Szczecin, Poland.ORCID https://orcid.org/0000-0002-2649-5967
Emese MihalyDepartment of Internal Medicine, Semmelweis University, Budapest, Hungary.
Lars K MunckDepartment of Gastroenterology, Zealand University Hospital, Koege, Denmark.
Ann-Elisabeth OstvikDepartment of Clinical and Molecular Medicine, NTNU: Norwegian University of Science and Technology, Trondheim, Norway.
Árpád V Patai2nd Department of Medicine, Semmelweis University, Budapest, Hungary.ORCID https://orcid.org/0000-0003-1863-5971
Plamen PenchevDepartment of Gastroenterology, Medical University of Sofia, University Hospital Tsaritsa Yoanna-ISUL, Sofia, Bulgaria.
Karolina Skonieczna-ŻydeckaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, Szczecin, Poland.
Bas VerhaeghDepartment of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
Andreas MünchDepartment of Gastroenterology and Hepatology in Linköping, Linköping University, Linköping, Sweden.
Linköping University · SEMútua Terrassa · ESPomeranian Medical University · PLQueen Giovanna Hospital · BGSemmelweis University · HUUniversity of Copenhagen · DKCentre Hospitalier de Valence · FRCopenhagen University Hospital · DKEdinburgh Royal Infirmary · GBHebron University · PSHospital de São João · PTHospital General de Tomelloso · ESKlinikum Region Hannover · DELithuanian University of Health Sciences · LTMaastricht University · NLMonash University · AUNorwegian University of Science and Technology · NOÖrebro University · SEÖrebro University Hospital · SERegionshospitalet Silkeborg · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMicroscopic colitis is a chronic inflammatory bowel disease characterised by normal or almost normal endoscopic appearance of the colon, chronic watery, nonbloody diarrhoea and distinct histological abnormalities, which identify three histological subtypes, the collagenous colitis, the lymphocytic colitis and the incomplete microscopic colitis. With ongoing uncertainties and new developments in the clinical management of microscopic colitis, there is a need for evidence-based guidelines to improve the medical care of patients suffering from this disorder.

methodsGuidelines were developed by members from the European Microscopic Colitis Group and United European Gastroenterology in accordance with the Appraisal of Guidelines for Research and Evaluation II instrument. Following a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation methodology was used to assess the certainty of the evidence. Statements and recommendations were developed by working groups consisting of gastroenterologists, pathologists and basic scientists, and voted upon using the Delphi method.

resultsThese guidelines provide information on epidemiology and risk factors of microscopic colitis, as well as evidence-based statements and recommendations on diagnostic criteria and treatment options, including oral budesonide, bile acid binders, immunomodulators and biologics. Recommendations on the clinical management of microscopic colitis are provided based on evidence, expert opinion and best clinical practice.

conclusionThese guidelines may support clinicians worldwide to improve the clinical management of patients with microscopic colitis.

Indexed as

budesonidediarrhoeainflammatory bowel diseasemicroscopic colitis

Identifiers

PMID33619914
PMCPMC8259259
OpenAlexW3080354643

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.