Evidence map›Paper›PMID 33619802›Full record

ArticleMagnetic resonance in medicine2021

Super-resolution head and neck MRA using deep machine learning.

Ioannis Koktzoglou, Rong Huang, William J Ankenbrandt, Matthew T Walker, Robert R Edelman

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. High Resolution TOF-MRA Using Compressed Sensing-based Deep Learning Image Reconstruction for the Visualization of Lenticulostriate Arteries: A Preliminary Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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  11. Current State of Artificial Intelligence in Clinical Applications for Head and Neck MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  12. Article
  13. Deep Learning and Its Application to Function Approximation for MR in Medicine: An Overview.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ioannis KoktzoglouDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.ORCID 0000-0001-9335-2010
Rong HuangDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
William J AnkenbrandtDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
Matthew T WalkerDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
Robert R EdelmanDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.ORCID 0000-0002-0013-8822
NorthShore University HealthSystem · USNorthwestern University · US

Funding

Rapid Real-Time MR Angiography of Suspected StrokeR01EB027475 · NIBIB · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI KOKTZOGLOU, IOANNIS · 2018 to 2021
$1.9M
NIBIB NIH HHS R01 EB027475
6 · The paper itself

Abstract

purposeTo probe the feasibility of deep learning-based super-resolution (SR) reconstruction applied to nonenhanced MR angiography (MRA) of the head and neck.

methodsHigh-resolution 3D thin-slab stack-of-stars quiescent interval slice-selective (QISS) MRA of the head and neck was obtained in eight subjects (seven healthy volunteers, one patient) at 3T. The spatial resolution of high-resolution ground-truth MRA data in the slice-encoding direction was reduced by factors of 2 to 6. Four deep neural network (DNN) SR reconstructions were applied, with two based on U-Net architectures (2D and 3D) and two (2D and 3D) consisting of serial convolutions with a residual connection. SR images were compared to ground-truth high-resolution data using Dice similarity coefficient (DSC), structural similarity index measure (SSIM), arterial diameter, and arterial sharpness measurements. Image review of the optimal DNN SR reconstruction was done by two experienced neuroradiologists.

resultsDNN SR of up to twofold and fourfold lower-resolution (LR) input volumes provided images that resembled those of the original high-resolution ground-truth volumes for intracranial and extracranial arterial segments, and improved DSC, SSIM, arterial diameters, and arterial sharpness relative to LR volumes (P < .001). The 3D DNN SR outperformed 2D DNN SR reconstruction. According to two neuroradiologists, 3D DNN SR reconstruction consistently improved image quality with respect to LR input volumes (P < .001).

conclusionDNN-based SR reconstruction of 3D head and neck QISS MRA offers the potential for up to fourfold reduction in acquisition time for neck vessels without the need to commensurately sacrifice spatial resolution.

Indexed as

Deep LearningMagnetic Resonance AngiographyHumansImaging, Three-DimensionalMachine LearningNeckdeep learningheadMRAnecksuper-resolution

Identifiers

PMID33619802
PMCPMC8034362
OpenAlexW3132466875

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.