Evidence map›Paper›PMID 33619761›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2021

Childhood psychopathology mediates associations between childhood adversities and multiple health risk behaviours in adolescence: analysis using the ALSPAC birth cohort.

David Troy, Abigail Russell, Judi Kidger, Caroline Wright

Open access · hybridAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

David TroySchool of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0003-0897-2704
Abigail RussellChildren and Young People's Mental Health Research Collaboration, College of Medicine and Health, University of Exeter, Exeter, UK.ORCID 0000-0002-2903-6264
Judi KidgerSchool of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Caroline WrightSchool of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
University of Bristol · GBUniversity of Exeter · GB

Funding

Cancer Research UK 23895Cancer Research UK C60153/A23895Medical Research Council 092731Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MR/R004889/1MRF_ MRF-058-0002-RG-MARSWellcome TrustWellcome Trust 217065/Z/19/ZWellcome Trust WT087640MA
6 · The paper itself

Abstract

backgroundChildhood adversity strongly predicts adolescent multiple health risk behaviours (MRBs) such as alcohol/tobacco use, self-harm and physical inactivity, and both adversities and MRBs are associated with premature mortality and several chronic health conditions that are among the leading causes of death in adults. It is therefore important to understand the relationship between adversities and MRBs and what could mediate any association. The aim of this study was to explore whether childhood psychopathology mediates associations between adversities and MRBs.

methodsParticipants were young people in the Avon Longitudinal Study of Parents and Children (ALSPAC) (N = 5,799). Using structural equation modelling, we explored the associations between adversities before 9 years and MRBs at age 16 years. We also explored potential mediating pathways through dimensional psychopathology measured by the Strength and Difficulties Questionnaire subscales at age 12 years.

resultsThere were strong positive associations between adversities and MRBs (β .25, 95% CI 0.20, 0.31, p < .001) suggesting that each additional adversity is associated with a 0.25 increase in number of MRBs out of 13 total risk behaviours. We found robust evidence of mediating pathways from adversities through conduct problems (β .05, 95% CI 0.03, 0.06, p < .001), hyperactivity/inattention (β .02, 95% CI 0.01, 0.03, p < .001) and peer relationship problems (β -.02, 95% CI -0.03, -0.02, p < .001) to MRBs.

conclusionsIncreased conduct problems and hyperactivity/inattention appear to partially explain the relationship between adversities and MRBs. Peer relationship problems also appear to reduce the association between adversities and MRBs, and further research is needed to understand how to encourage peer connectivity without increasing risk of MRBs. These results suggest that interventions aimed at reducing MRBs among those exposed to childhood adversities could focus on prevention of behavioural problems.

Indexed as

Mental DisordersSelf-Injurious BehaviorAdolescentAdultChildHealth Risk BehaviorsHumansLongitudinal StudiesParentsRisk FactorsadolescenceAdverse childhood experiencesALSPACmediation analysismultiple health risk behaviourspsychosocial attributesstructural equation modellingUK birth cohort study

Identifiers

PMID33619761
PMCPMC8532527
OpenAlexW3035144260

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.