Evidence map›Paper›PMID 33619646›Full record

ArticleBrain imaging and behavior2021

Multivariate machine learning-based language mapping in glioma patients based on lesion topography.

Nan Zhang, Binke Yuan, Jing Yan, Jingliang Cheng, Junfeng Lu, Jinsong Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Brain imaging and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nan Zhang *Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Anhui, Hefei, China.ORCID http://orcid.org/0000-0002-9960-6859
Binke Yuan *Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China.ORCID http://orcid.org/0000-0002-9839-8453
Jing Yan *Department of MRI , The First Affiliated Hospital of Zhengzhou University , Zhengzhou, China.
Jingliang ChengDepartment of MRI , The First Affiliated Hospital of Zhengzhou University , Zhengzhou, China.
Junfeng LuGlioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Fudan University, Shanghai, China. junfeng_lu@fudan.edu.cn.ORCID http://orcid.org/0000-0002-6091-5742
Jinsong WuGlioma Surgery Division, Neurologic Surgery Department, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-7854-9798
First Affiliated Hospital of Zhengzhou University · CNFudan University · CNSouth China Normal University · CNUniversity of Science and Technology of China · CN

Funding

China Postdoctoral Science Foundation 2018M640825Fundamental Research Funds for the Central Univerisities WK9110000133Guangdong key basic research grant 2018B030332001Guangdong Pearl River Talents Plan 2016ZT06S220National Natural Science Foundation of China 81401395Research Projects of Henan Higher Education 18A320077Shanghai Municipal Science and Technology Major Project 2018SHZDZX03Shanghai Young Talents in Health 2017YQ014Shenzhen Double Chain Grant [2018]256The Scientific and Technological Research Projects of Henan Province 192102310123
6 · The paper itself

Abstract

Diffusive and progressive tumor infiltration within language-related areas of the brain induces functional reorganization. However, the macrostructural basis of subsequent language deficits is less clear. To address this issue, lesion topography data from 137 preoperative patients with left cerebral language-network gliomas (81 low-grade gliomas and 56 high-grade gliomas), were adopted for multivariate machine-learning-based lesion-language mapping analysis. We found that tumor location in the left posterior middle temporal gyrus-a bottleneck where both dorsal and ventral language pathways travel-predicted deficits of spontaneous speech (cluster size = 1356 mm

Indexed as

Brain NeoplasmsGliomaBrain MappingHumansLanguageMachine LearningMagnetic Resonance ImagingHigh‐grade gliomaLanguageLow‐grade gliomaMachine learningStructural MRI

Identifiers

PMID33619646
OpenAlexW3130265915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.