Evidence map›Paper›PMID 33619599›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases.

Jad S Husseini, Bárbara Juarez Amorim, Angel Torrado-Carvajal, Vinay Prabhu, David Groshar, Lale Umutlu, Ken Herrmann, Lina García Cañamaque, José Ramón García Garzón, William E Palmer and 23 more

Open access · greenAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 10 countries.

Jad S HusseiniDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Bárbara Juarez AmorimDivision of Nuclear Medicine, Department of Radiology, School of Medical Sciences,, State University of Campinas, Campinas, Brazil.
Angel Torrado-CarvajalAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Vinay PrabhuDepartment of Radiology, NYU Langone Health, New York, NY, USA.
David GrosharDepartment of Nuclear Medicine, Assuta Medical Center, Tel Aviv, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lale UmutluDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University Hospital Essen, Essen, Germany.
Lina García CañamaqueDepartment of Nuclear Medicine, Hospital Universitario Madrid Sanchinarro, Madrid, Spain.
José Ramón García GarzónDepartment of Nuclear Medicine, CETIR-ERESA, University of Barcelona, Barcelona, Spain.
William E PalmerDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Pedram HeidariDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Tiffany Ting-Fang ShihDepartment of Radiology and Medical Imaging, National Taiwan University College of Medicine and Hospital, Taipei City, Taiwan.
Jacob SosnaDepartment of Radiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Cristina MatushitaDepartment of Nuclear Medicine, Hospital São Lucas of Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Juliano CerciDepartment of Nuclear Medicine, Quanta Diagnóstico Nuclear, Curitiba, Brazil.
Marcelo QueirozDepartment of Radiology and Oncology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Valdair Francisco MugliaDepartment of Medical Images, Radiation Therapy and Oncohematology, Ribeirao Preto Medical School, Hospital Clinicas, University of São Paulo, Ribeirão Prêto, Brazil.
Marcello H Nogueira-BarbosaDepartment of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School. University of São Paulo (USP), Ribeirão Prêto, Brazil.
Ronald J H BorraMedical Imaging Center, University Medical Center Groningen, Groningen, The Netherlands.
Thomas C KweeMedical Imaging Center, University Medical Center Groningen, Groningen, The Netherlands.
Andor W J M GlaudemansMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands.
Laura EvangelistaDepartment of Clinical and Experimental Medicine, University of Padova, Padua, Italy.
Marco SalvatoreDepartment of Radiology and Nuclear Medicine, Università Suor Orsola Benincasa di Napoli, Naples, Italy.
Alberto CuocoloDepartment of Radiology and Nuclear Medicine, Institute for Hospitalization and Healthcare (IRCCS) SDN, Istituto di Ricerca, Naples, Italy.
Andrea SoricelliDepartment of Radiology and Nuclear Medicine, Institute for Hospitalization and Healthcare (IRCCS) SDN, Istituto di Ricerca, Naples, Italy.
Christian HeroldDepartment of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna General Hospital, Vienna, Austria.
Andrea LaghiDepartment of Radiology, University of Rome "La Sapienza", Rome, Italy.
Marius MayerhoeferDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Umar MahmoodDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Ciprian CatanaAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Heike E Daldrup-LinkDepartment of Radiology, Stanford University, Stanford, CA, USA.
Bruce RosenAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Onofrio A CatalanoDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA. ocatalano@mgh.harvard.edu.ORCID http://orcid.org/0000-0001-7733-4138
Massachusetts General Hospital · USUniversity Medical Center Groningen · NLEssen University Hospital · DEUniversidade de São Paulo · BREndesa (Spain) · ESHadassah Medical Center · ILHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital Universitario HM Sanchinarro · ESMemorial Sloan Kettering Cancer Center · USNational Taiwan University Hospital · TWNYU Langone Health · USParthenope University of Naples · ITPontifícia Universidade Católica do Rio Grande do Sul · BRQuanta Computer (China) · CNSapienza University of Rome · ITSDN Istituto di Ricerca Diagnostica e Nucleare · ITStanford University · USTel Aviv University · ILUniversidade Estadual de Campinas (UNICAMP) · BRUniversidad Rey Juan Carlos · ES

Funding

Enhancing the therapeutic effect of receptor radionuclide therapy in neuroendocrine tumors by somatostatin receptor upregulationK08CA249047 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HEIDARI, PEDRAM · 2020 to 2024
$1.3M
NCI NIH HHS K08 CA249047
6 · The paper itself

Abstract

backgroundMR is an important imaging modality for evaluating musculoskeletal malignancies owing to its high soft tissue contrast and its ability to acquire multiparametric information. PET provides quantitative molecular and physiologic information and is a critical tool in the diagnosis and staging of several malignancies. PET/MR, which can take advantage of its constituent modalities, is uniquely suited for evaluating skeletal metastases. We reviewed the current evidence of PET/MR in assessing for skeletal metastases and provided recommendations for its use.

methodsWe searched for the peer reviewed literature related to the usage of PET/MR in the settings of osseous metastases. In addition, expert opinions, practices, and protocols of major research institutions performing research on PET/MR of skeletal metastases were considered.

resultsPeer-reviewed published literature was included. Nuclear medicine and radiology experts, including those from 13 major PET/MR centers, shared the gained expertise on PET/MR use for evaluating skeletal metastases and contributed to a consensus expert opinion statement. [18F]-FDG and non [18F]-FDG PET/MR may provide key advantages over PET/CT in the evaluation for osseous metastases in several primary malignancies.

conclusionPET/MR should be considered for staging of malignancies where there is a high likelihood of osseous metastatic disease based on the characteristics of the primary malignancy, hight clinical suspicious and in case, where the presence of osseous metastases will have an impact on patient management. Appropriate choice of tumor-specific radiopharmaceuticals, as well as stringent adherence to PET and MR protocols, should be employed.

Indexed as

Positron Emission Tomography Computed TomographyFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPositron-Emission TomographyRadiopharmaceuticalsFluorodeoxyglucose F18RadiopharmaceuticalsMetastasesMROsseousPETPET/MRPET/MRISkeletal

Identifiers

PMID33619599
PMCPMC8240455
OpenAlexW3129491862

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.