ArticleResearch square2021
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models.
Open access · greenAbstract readPreprint
In one paragraph
Article in Research square, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 20 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
50 authors at 9 institutions in 3 countries.
P MaisonnasseUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
Y AldonDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
A MarcUniversité de Paris, INSERM, IAME, F-75018 Paris, France.
R MarlinUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
N Dereuddre-BosquetUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
N A KuzminaDepartment of Pathology, University of Texas Medical Branch at Galveston, Texas, USA.
A W FreynDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
J L SnitselaarDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
A GonçalvesUniversité de Paris, INSERM, IAME, F-75018 Paris, France.
T G CanielsDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
J A BurgerDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
M PonimanDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
V ChesnaisLife and Soft, 92350 Le Plessis-Robinson, France.
S DiryLife and Soft, 92350 Le Plessis-Robinson, France.
A IershovLife and Soft, 92350 Le Plessis-Robinson, France.
A J RonkDepartment of Pathology, University of Texas Medical Branch at Galveston, Texas, USA.
S JangraDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
R RathnasingheDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
Pjm BrouwerDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
Tpl BijlDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
J van SchootenDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
M BrinkkemperDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
H LiuDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
M YuanDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
C E MireGalveston National Laboratory, Texas, USA.
M J van BreemenDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
V ContrerasUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
T NaninckUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
J LemaîtreUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
N KahlaouiUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
F RelouzatUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
C ChaponUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
R Ho Tsong FangUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
C McDanalDuke Human Vaccine Institute & Department of Surgery, Durham, NC 27710, USA.
M Osei-TwumNexelis, Laval, Québec, Canada.
N St-AmantNexelis, Laval, Québec, Canada.
L GagnonNexelis, Laval, Québec, Canada.
D C MontefioriDuke Human Vaccine Institute & Department of Surgery, Durham, NC 27710, USA.
I A WilsonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
E GinouxLife and Soft, 92350 Le Plessis-Robinson, France.
G J de BreeInternal Medicine of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
A García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
M SchotsaertDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
L CoughlanDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York (NY), USA.
A BukreyevDepartment of Pathology, University of Texas Medical Branch at Galveston, Texas, USA.
S van der WerfMolecular Genetics of RNA Viruses, Department of Virology, Institut Pasteur, CNRS UMR 3569, Université de Paris, Paris, France.
J GuedjUniversité de Paris, INSERM, IAME, F-75018 Paris, France.
R W SandersDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
M J van GilsDepartments of Medical Microbiology of the Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection and Immunity, 1105 AZ, Amsterdam, The Netherlands.
R Le GrandUniversité Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Paris, France.
Inserm · FRAmsterdam University Medical Centers · NLIcahn School of Medicine at Mount Sinai · USExelis (United States) · USScripps Research Institute · USDuke University · USThe University of Texas Medical Branch at Galveston · USInstitut Pasteur · FRUniversity of Maryland, Baltimore · US
Funding
SARS-CoV adaptations through a Systems Biology Lens (SYBIL)U19AI135972 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Adolfo Garcia-Sastre · 2018 to 2026
$27.2MExosome-display as a strategy to enhance the immunogenicity of SARS-CoV-2 vaccines based on adenoviral vectorsR21AI157606 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI COUGHLAN, LYNDA · 2020 to 2020
$425kNIAID NIH HHS HHSN272201400008CNIAID NIH HHS R21 AI157606NIAID NIH HHS U19 AI135972
Abstract
One year into the Coronavirus Disease 2019 (COVID-19) pandemic caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), effective treatments are still needed
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.