Evidence map›Paper›PMID 33619447›Full record

ReviewCurrent pharmacology reports2021

Efficacy and Safety of New and Emerging Drugs for COVID-19: Favipiravir and Dexamethasone.

Shivani Sood, Gurpreet Kaur Bhatia, Prachi Seth, Pawan Kumar, Jagjit Kaur, Vidisha Gupta, Sandeep Punia, Hardeep Singh Tuli

Open access · bronzeAbstract readReview
In one paragraph

Review in Current pharmacology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Clinical efficacy of antiviral agents against coronavirus disease 2019: A systematic review of randomized controlled trials.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2021
    Pooled it
  2. Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Favipiravir exposure and pregnancy outcome of COVID-19 patients.European journal of obstetrics, gynecology, and reproductive biology · 2022
    Article
  9. Current trends in diagnosis and treatment strategies of COVID-19 infection.Environmental science and pollution research international · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Shivani SoodDepartment of Biotechnology, Mukand Lal National College, Yamuna Nagar, India.
Gurpreet Kaur BhatiaDepartment of Physics, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133207 India.
Prachi SethDepartment of Biotechnology, Mukand Lal National College, Yamuna Nagar, India.
Pawan KumarInstitute of Plant Sciences, Agricultural Research Organisation (ARO), 7505101 Rishon LeZion, Israel.
Jagjit KaurGraduate School of Biomedical Engineering, ARC Centre of Excellence in Nanoscale Biophotonics (CNBP), Faculty of Engineering, The University of New South Wales, Sydney, 2052 Australia.
Vidisha GuptaDepartment of Zoology, Mukand Lal National College, Yamuna Nagar, India.
Sandeep PuniaDepartment of Biotechnology, Multani Mal Modi College, Patiala, India.
Hardeep Singh TuliDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133207 India.ORCID 0000-0003-1155-0094
Maharishi Markandeshwar University, Mullana · INAgricultural Research Organization · ILUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe widespread respiratory disease of virus known as severe acute respiratory syndrome-coronavirus 2019 (SAR-CoV-2) had infected more than 200 countries and caused pandemic and havoc in the world. RECENT

findingsThe genome of the virus was sequenced rapidly to study its mechanism, epidemiology, drugs, and vaccines. Many drugs and vaccines are being studied by researchers to treat and prevent the SARS-CoV-2. Favipiravir and dexamethasone are repurposed drugs which showed therapeutic potential and pharmaceutical efficacy against SARS-CoV-2. SUMMARY: The review describes the path of favipiravir and dexamethasone from chemistry to mechanisms of action to combat SARS-CoV-2. In addition, the potential side effects are also summarized to study their potential to control corona virus 2019

Indexed as

Coronavirus 2019DexamethasoneEpidemiologyFavipiravirSevere acute respiratory syndrome

Identifiers

PMID33619447
PMCPMC7889701
OpenAlexW3132770841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.