Evidence map›Paper›PMID 33619129›Full record

ReviewBMJ case reports2021

Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm.

Susruta Manivannan, Feras Sharouf, George Lammie, Paul Leach

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Susruta ManivannanNeurosurgery, Southampton University Hospitals NHS Trust, Southampton, UK.ORCID http://orcid.org/0000-0001-5905-2073
Feras SharoufSchool of Medicine, Cardiff University, Cardiff, UK sharouffh@cardiff.ac.uk.ORCID http://orcid.org/0000-0002-3034-3392
George LammieSchool of Medicine, Cardiff University, Cardiff, UK.
Paul LeachDepartment of Neurosurgery, University Hospital of Wales, Cardiff University, Cardiff, UK.
Cardiff University · GBUniversity Hospital of Wales · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

Indexed as

Brain NeoplasmsNeuroendocrine TumorsHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalScalpendocrine cancerneurosurgery

Identifiers

PMID33619129
PMCPMC7903122
OpenAlexW3132983045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.