ArticleProceedings of the National Academy of Sciences of the United States of America2021
An increase in dendritic plateau potentials is associated with experience-dependent cortical map reorganization.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Subicular plateaus signal reward locations during goal-directed behavior.Cell reports · 2026Article
- Subicular Plateaus Signal Reward Locations during Goal-Directed Behavior.bioRxiv : the preprint server for biology · 2026Article
- Context-dependent NMDA receptor dysfunction predicts seizure treatment in mice with human GluN1 variant.iScience · 2026Article
- Plateau potentials are instructive signals for behavioral timescale synaptic plasticity in the neocortex.bioRxiv : the preprint server for biology · 2025Article
- Thalamocortical feedback selectively controls pyramidal neuron excitability.Nature communications · 2025Article
- The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Posteromedial thalamic nucleus activity significantly contributes to perceptual discrimination.PLoS biology · 2022Article
- Assessing Local and Branch-specific Activity in Dendrites.Neuroscience · 2022Article
- Corticothalamic Pathways From Layer 5: Emerging Roles in Computation and Pathology.Frontiers in neural circuits · 2021Review
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Authors and funding
6 authors.
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Abstract
The organization of sensory maps in the cerebral cortex depends on experience, which drives homeostatic and long-term synaptic plasticity of cortico-cortical circuits. In the mouse primary somatosensory cortex (S1) afferents from the higher-order, posterior medial thalamic nucleus (POm) gate synaptic plasticity in layer (L) 2/3 pyramidal neurons via disinhibition and the production of dendritic plateau potentials. Here we address whether these thalamocortically mediated responses play a role in whisker map plasticity in S1. We find that trimming all but two whiskers causes a partial fusion of the representations of the two spared whiskers, concomitantly with an increase in the occurrence of POm-driven
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