Evidence map›Paper›PMID 33619028›Full record

ArticleInfection and immunity2021

Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization.

Q C Truong-Bolduc, Y Wang, D C Hooper

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Phenazine-1 carboxylic acid ofAntimicrobial agents and chemotherapy · 2024
    Article
  7. Review
  8. Role ofJournal of bacteriology · 2022
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Q C Truong-BolducDivision of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Y WangDivision of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
D C HooperDivision of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA dhooper@mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI Michael S Gilmore · 2009 to 2026
$39.4M
Quinolone and multidrug resistance in Staphylococcus aureusR37AI023988 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HOOPER, DAVID C · 2008 to 2017
$4.1M
NIAID NIH HHS P01 AI083214NIAID NIH HHS R37 AI023988
6 · The paper itself

Abstract

The

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, NeoplasmHost-Pathogen InteractionsHumansMembrane Transport ProteinsStaphylococcal InfectionsStaphylococcus aureusStructure-Activity RelationshipTetracyclineAnti-Bacterial AgentsBacterial ProteinsMembrane Transport ProteinsTetracyclineCD36efflux pumpsinternalizationresistance to tetracyclineStaphylococcus aureusTet38

Identifiers

PMID33619028
PMCPMC8091097
OpenAlexW3130151303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.