ArticleBMC pregnancy and childbirth2021
Gestational systolic blood pressure trajectories and risk of adverse maternal and perinatal outcomes in Chinese women.
Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Maternal Consumption of Ultra-Processed Foods-Rich Diet and Perinatal Outcomes: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- DHA, nutrient intake, and maternal characteristics as predictors of pregnancy outcomes in a randomised clinical trial of DHA supplementation.Clinical nutrition (Edinburgh, Scotland) · 2023Trial
- Blood pressure trajectories during pregnancy, labor, and postpartum period: a multicenter study in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Observational
- Association of dynamic blood pressure trajectory during pregnancy with adverse birth outcomes: a large prospective cohort study in China.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Dose-response relationship between early pregnancy blood pressure and gestational diabetes mellitus based on propensity score matching: a retrospective study.BMC pregnancy and childbirth · 2026Article
- Hypertensive disorders of pregnancy: incidence, anthropometric, hemodynamic, and urinary trajectories in a Colombian cohort.Frontiers in physiology · 2026Article
- A steep-increasing blood pressure trajectory from early pregnancy is associated with birth outcomes in the EDEN mother-child cohort.Journal of hypertension · 2025Article
- A study on the correlation between pregnancy risk factors and birth outcomes.Scientific reports · 2025Article
- Blood Pressure and Late Pregnancy Circulating miRNAs in the MADRES Study.Journal of the American Heart Association · 2025Article
- Examining maternal and fetal outcomes across various subtypes of hypertension during pregnancy.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Association between three-timepoint maternal blood pressure trajectories during pregnancy and low birth weight: a longitudinal study based on NHANES 2005-2006.Frontiers in pediatrics · 2025Article
- Interactions between Hypertension and Breastfeeding: What Do We Know?Current hypertension reviews · 2025Article
- First trimester plasma PER- AND Polyfluoroalkyl Substances (PFAS) and blood pressure trajectories across the second and third trimesters of pregnancyEnvironment international · 2024Article
- Article
- Alterations in the Gut Microbiome and Metabolisms in Pregnancies with Fetal Growth Restriction.Microbiology spectrum · 2023Article
- Posttraumatic stress disorder, diurnal cortisol, and ambulatory blood pressure in early and late pregnancy.Journal of traumatic stress · 2023Article
- Hypertensive disorders of pregnancy: definition, management, and out-of-office blood pressure measurement.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Review
- Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals, and Pharmacotherapy: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2022Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAssociations between trajectories of systolic blood pressure (SBP) during pregnancy and pregnant outcomes remain unclear and disparate.
methodsData of 20,353 mothers without chronic hypertension and who delivered live singletons between January, 2014 and November, 2019, was extracted from Taicang register-based cohort. Based on SBP measured during 10 to 40 weeks of gestation, SBP trajectories were explored using latent class growth mixture model, and their associations with maternal and neonatal outcomes were assessed by logistic regression analyses.
resultsSix heterogeneous SBP trajectories were identified: low delayed-increasing (7.47%), low reverse-increasing (21.88%), low-stable (19.13%), medium-stable (21.64%), medium reverse-increasing (16.47%), and high stable (13.41%) trajectories. The high-stable trajectory had SBP around 125 mmHg in the 10th gestational week, and increased slightly onwards. When compared with the low-stable trajectory, the high-stable trajectory had maximally adjusted odds ratio (95% confidence interval) of 5.28 (2.76-10.10), 1.30 (1.13-1.50), 1.53 (1.12-2.08), 1.32 (1.06-1.65) and 1.64 (1.08-2.48) for gestational hypertension (GH), early-term delivery (ETD), preterm delivery (PTD), small for gestational age and low birth weight (LBW), respectively. Besides, the medium reverse-increasing trajectory showed significantly increased risk of GH and ETD, while the medium-stable trajectory had significantly elevated risk of ETD and PTD. Notably, SBP trajectories slightly but significantly improved risk discrimination of GH, ETD and LBW, over traditional risk factors.
conclusionWomen with different SBP trajectories were at varied risk of adverse maternal and fetal outcomes. Meanwhile, our study suggested that BP monitoring during pregnancy is necessary, especially for women with high SBP in early pregnancy or upward trajectory.
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