Evidence map›Paper›PMID 33618705›Full record

ArticleBMC complementary medicine and therapies2021

Chemical composition, in vitro antioxidant, anticholinesterase, and antidiabetic potential of essential oil of Elaeagnus umbellata Thunb.

Nausheen Nazir, Muhammad Zahoor, Faheem Uddin, Mohammad Nisar

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Antiangiogenic potential ofOpen medicine (Warsaw, Poland) · 2025
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  7. Antioxidants (Basel, Switzerland) · 2024
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  10. Saudi journal of biological sciences · 2023
    Review
  11. Article
  12. Molecules (Basel, Switzerland) · 2022
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  13. Article
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  15. Antioxidant, Antidiabetic, and Antibacterial Potentials and Chemical Composition ofAdvances in pharmacological and pharmaceutical sciences · 2022
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  16. Article
  17. Antioxidants Isolated fromMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nausheen NazirDepartment of Biochemistry, University of Malakand, Chakdara Dir (L), Khyber Pakhtunkhwa, Pakistan. nausheen.nazir@uom.edu.pk.ORCID http://orcid.org/0000-0003-4289-3970
Muhammad ZahoorDepartment of Biochemistry, University of Malakand, Chakdara Dir (L), Khyber Pakhtunkhwa, Pakistan.
Faheem UddinDepartment of Electrical Engineering, Sarhad University of Science and Information Technology, Peshawar, Pakistan.
Mohammad NisarDepartment of Botany, University of Malakand, Chakdara Dir (L), Khyber Pakhtunkhwa, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElaeagnus umbellata Thunb. (autumn olive) is a high valued medicinal plant. It belongs to Elaeagnaceae family and is widely distributed in Himalayan regions of Pakistan. In the present study essential oil were extracted from the fruit of this plant and their antioxidant, anticholinesterase and antidiabetic potentials were also evaluated.

methodsEssential oils were extracted from the fruit of E. umbellata using hydro-distillation method and were characterized by GC-MS. The extracted oil were tested for its antioxidant, anticholinesterase, and antidiabetic potentials using standard protocols.

resultsAbout 68 compounds were identified by GC-MS. The extracted oil exhibited a fairly high free radical scavenging activities against DPPH and ABTS radicals with IC

conclusionEssential oil extracted from the fruits of E. umbellata exhibited reasonable antioxidant, anticholinesterase, and antidiabetic potentials that could be used as alternative medicine in treating diabetes and neurodegenerative disorders. However, further studies are needed to isolate responsible compounds and evaluate the observed potential in animal models.

Indexed as

alpha-Amylasesalpha-GlucosidasesAntioxidantsCholinesterase InhibitorsElaeagnaceaeEnzyme InhibitorsGas Chromatography-Mass SpectrometryHumansHypoglycemic AgentsOils, VolatilePakistanPlant Extractsalpha-Amylasesalpha-GlucosidasesAntioxidantsCholinesterase InhibitorsEnzyme InhibitorsHypoglycemic AgentsOils, VolatilePlant ExtractsABTSAnti-cholinesteraseDPPHGC-MSα-Glucosidase and α-amylase

Identifiers

PMID33618705
PMCPMC7898454

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.