ArticleBMC genomics2021
Transcriptome sequencing and metabolome analysis of food habits domestication from live prey fish to artificial diets in mandarin fish (Siniperca chuatsi).
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 47 citations in OpenAlex.
- Altered immunometabolic responses to Aeromonas hydrophila infection in artificial diet-fed mandarin fish (Siniperca chuatsi).Fish physiology and biochemistry · 2026Article
- A comparative analysis of serum biochemistry, gene expression, and gut microbiota in domestication-susceptible and domestication-resistant mandarin fish (Siniperca chuatsi).Fish physiology and biochemistry · 2026Article
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- Dietary responses of taste receptor genes to plant-based diets in farmed fish: A literature review.Open veterinary journal · 2026Review
- Integrated Pathogen-Host Analysis ofMicroorganisms · 2025Article
- Stress Response ofAnimals : an open access journal from MDPI · 2025Article
- Integrated transcriptome and metabolome analyses unraveled critical roles of small intestine during the weaning period of Vespertilio sinensis.BMC genomics · 2025Article
- Bacterial diseases in Siniperca chuatsi: status and therapeutic strategies.Veterinary research communications · 2024Review
- Molecular Cloning of theGenes · 2024Article
- Multi-Omics Reveals the Effects ofAntioxidants (Basel, Switzerland) · 2024Article
- Proteomics-Based Investigation of Different Live Prey Administered to Freshwater Dark Sleeper (Metabolites · 2024Article
- Integrated transcriptomic and proteomic analyses reveal the mechanism of easy acceptance of artificial pelleted diets during food habit domestication in Largemouth bass (Micropterus salmoides).Scientific reports · 2023Article
- Preliminary study on toxicological mechanism of golden cuttlefish (Sepia esculenta) larvae exposed to cd.BMC genomics · 2023Article
- Transcriptome Reveals the Effects of Early Weaning on Lipid Metabolism and Liver Health of Yangtze Sturgeon (International journal of molecular sciences · 2022Article
- Whole-genome resequencing and bisulfite sequencing provide new insights into the feeding habit domestication in mandarin fish (Frontiers in genetics · 2022Article
- Transcriptomic assessment of dietary fishmeal partial replacement by soybean meal and prebiotics inclusion in the liver of juvenile Pacific yellowtail (Seriola lalandi).Molecular biology reports · 2021Article
- Probiotics Improve Eating Disorders in Mandarin Fish (Microorganisms · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
backgroundAs economical traits, food habits domestication can reduce production cost in aquaculture. However, the molecular mechanism underlying food habits domestication has remained elusive. Mandarin fish (Siniperca chuatsi) only feed on live prey fish and refuse artificial diets. In the present study, we domesticated mandarin fish to feed on artificial diets. The two groups were obtained, the fish did not eat artificial diets or ate artificial diets during all of the three domestication processes, named Group W or X, respectively.
resultsUsing transcriptome and metabolome analysis, we investigated the differentially expressed genes and metabolites between the two groups, and found three common pathways related to food habit domestication, including retinol metabolism, glycerolipid metabolism, and biosynthesis of unsaturated fatty acids pathways. Furthermore, the western blotting and bisulfite sequencing PCR analysis were performed. The gene expression of TFIIF and histone methyltransferase ezh1 were significantly increased and decreased in the fish of Group X, respectively. The total DNA methylation levels of TFIIF gene and tri-methylation of histone H3 at lysine 27 (H3K27me3) were significantly higher and lower in the fish of Group X, respectively.
conclusionIt was speculated that mandarin fish which could feed on artificial diets, might be attributed to the lower expression of ezh1, resulting in the decreased level of H3K27me3 and increased level of DNA methylation of TFIIF gene. The high expression of TFIIF gene might up-regulate the expression of genes in retinol metabolism, glycerolipid metabolism and glycerophosphoric metabolism pathways. Our study indicated the relationship between the methylation of DNA and histone and food habits domestication, which might be a novel molecular mechanism of food habits domestication in animals.
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