Evidence map›Paper›PMID 33618632›Full record

ArticleAutophagy2021

TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation.

Chaofeng Tu, Haiyu Li, Xuyang Liu, Ying Wang, Wei Li, Lanlan Meng, Weili Wang, Yong Li, Dongyan Li, Juan Du and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Autophagy in ocular diseases: from mechanisms to therapeutic potential.Frontiers in cell and developmental biology · 2026
    Review
  5. Review
  6. Exploiting autophagy and related pathways: pioneering new horizons in cataract therapy.Apoptosis : an international journal on programmed cell death · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Effectors and effects of arginine methylation.Biochemical Society transactions · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Chaofeng TuInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Haiyu LiInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Xuyang LiuShenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Jinan University, Shenzhen, China.
Ying WangInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Wei LiState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0002-6235-0749
Lanlan MengClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China.
Weili WangInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Yong LiInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Dongyan LiInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Juan DuInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Guangxiu LuClinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, China.
Ge LinInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.
Yue-Qiu TanInstitute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, China.ORCID 0000-0002-8359-4654
Central South University · CNReproductive & Genetic Hospital CITIC-Xiangya · CNChinese Academy of Sciences · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In humans,

Indexed as

SpermatogenesisAnimalsAutophagosomesFibroblastsGene Expression ProfilingHumansLens, CrystallineLysosomesMiceRibonucleoproteinsRibonucleoproteinsTdrd7 protein, humanAcrosome biogenesisautophagylens developmentspermiogenesistbc1d20tdrd7

Identifiers

PMID33618632
PMCPMC8632297
OpenAlexW3187775937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.