Observational studyJournal of the American Heart Association2021
Associations of Job Strain, Stressful Life Events, and Social Strain With Coronary Heart Disease in the Women's Health Initiative Observational Study.
Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- The demands-control-support work stress model and risk of ischemic heart disease: causal inference based on observational epidemiology.Scandinavian journal of work, environment & health · 2026Pooled it
- The Impact of Job Strain on Occupational Access to Firearms and Firearm-Related Suicide Among US Workers.American journal of industrial medicine · 2026Article
- Examining the Association Between Occupational Strain and Risk of Angina Pectoris Among Older Working Adults in India Using Karasek's Job Demand Control Model.Research square · 2026Article
- Coronary Heart Disease Attributable to Psychosocial Stressors at Work.JACC. Advances · 2025Article
- Influence of occupational stress on breast cancer incidence in the Women's Health Initiative.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Observational
- Association of Evening Shifts, Night Shifts, and Consistent Overtime Exceeding 10 Hours per Day with Sudden Cardiac Arrest: A Case-Control Study.Journal of clinical medicine · 2024Article
- The Relationship between Job Strain and Ischemic Heart Disease Mediated by Endothelial Dysfunction Markers and Imaging.Medicina (Kaunas, Lithuania) · 2024Article
- Stressful life events, social support, and epigenetic aging in the Women's Health Initiative.Journal of the American Geriatrics Society · 2024Article
- Differences in cardiovascular risk factors associated with sex and gender identity, but not gender expression, in young, healthy cisgender adults.Frontiers in cardiovascular medicine · 2024Article
- Needs and demands for mHealth cardiac health promotion among individuals with cardiac diseases: a patient-centred design approach.European heart journal. Digital health · 2023Article
- Association Between Insomnia, Stress Events, and Other Psychosocial Factors and Incident Atrial Fibrillation in Postmenopausal Women: Insights From the Women's Health Initiative.Journal of the American Heart Association · 2023Article
- Sex differences in potential triggers of myocardial infarction.European heart journal open · 2023Article
- Be lucky.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Article
- Analysis of occupational stress and its correlation with oxidative-antioxidant levels among employees of a power grid enterprise in Guangdong.BMC psychiatry · 2022Article
- Pearls and Purple: The Dawn of a Modern Age.Journal of the American Heart Association · 2021Article
- Associations of Job Strain, Stressful Life Events, and Social Strain With Coronary Heart Disease in the Women's Health Initiative Observational Study.Journal of the American Heart Association · 2021Observational
- Assessment of Cardiovascular Risk Factors and Their Interactions in the Risk of Coronary Heart Disease in Patients with Type 2 Diabetes with Different Weight Levels, 2013-2018.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
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8 authors at 3 institutions in 1 country.
Funding
Abstract
Background The association between psychosocial stress and coronary heart disease (CHD) may be stronger in women than men and may differ across types of stressors. In this study, we assessed associations of psychosocial stressors, including job strain, stressful life events, and social strain with the incidence of CHD in women. Methods and Results We used longitudinal data from 80 825 WHI-OS (Women's Health Initiative Observational Study) participants with a mean age of 63.4 years (7.3 years) at baseline. Job strain was assessed through linkage of Standard Occupational Classification codes to the Occupational Information Network. Stressful life events and social strain were assessed via validated self-reported questionnaires. Cox proportional hazard models were used to evaluate associations of each stressor with CHD separately and jointly. A total of 3841 (4.8%) women developed CHD during an average of 14.7 years of follow-up. After adjustment for age, other stressors, job tenure, and socioeconomic factors, high stressful life events score was associated with a 12% increased CHD risk, and high social strain was associated with a 9% increased CHD risk. Job strain was not independently associated with CHD risk, but we observed a statistically significant interaction between job strain and social strain (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.