Evidence map›Paper›PMID 33618348›Full record

ArticleNature2021

Genomic insights into the formation of human populations in East Asia.

Chuan-Chao Wang, Hui-Yuan Yeh, Alexander N Popov, Hu-Qin Zhang, Hirofumi Matsumura, Kendra Sirak, Olivia Cheronet, Alexey Kovalev, Nadin Rohland, Alexander M Kim and 75 more

Open access · greenAbstract readHistorical Article
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 190 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
190citing papers in PubMed, 1 pooled it
59.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

190 citing papers in PubMed, 1 synthesis or guideline pooled it, 448 citations in OpenAlex.

  1. Pooled it
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  9. High-coverage ancient genomes reveal divergent population histories and prehistoric starch-related genetic variation in Japan.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  17. On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026
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  20. Genetic structure and admixture of the Yi and Qiang in southwestern China.Journal of Zhejiang University. Science. B · 2026
    Article

130 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

85 authors at 20 institutions in 9 countries.

Chuan-Chao Wang *Department of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China. wang@xmu.edu.cn.ORCID http://orcid.org/0000-0001-9628-0307
Hui-Yuan Yeh *School of Humanities, Nanyang Technological University, Nanyang, Singapore.
Alexander N Popov *Scientific Museum, Far Eastern Federal University, Vladivostok, Russia.
Hu-Qin Zhang *Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Hirofumi MatsumuraSchool of Health Science, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0001-5453-7987
Kendra SirakDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Olivia CheronetDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0001-6760-1204
Alexey KovalevInstitute of Archaeology, Russian Academy of Sciences, Moscow, Russia.ORCID http://orcid.org/0000-0003-2637-3131
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Alexander M KimDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Rebecca BernardosDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4625-3727
Dashtseveg TumenDepartment of Anthropology and Archaeology, National University of Mongolia, Ulaanbaatar, Mongolia.
Jing ZhaoKey Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Yi-Chang LiuInstitute of Archaeology, National Cheng Kung University, Tainan, Taiwan.
Jiun-Yu LiuDepartment of Anthropology, University of Washington, Seattle, WA, USA.
Matthew MahDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Ke WangDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0003-3935-8344
Zhao ZhangDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Nicole AdamskiDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Nasreen BroomandkhoshbachtDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5350-1608
Kimberly CallanDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-3170-8514
Francesca CandilioDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-4668-1361
Kellie Sara Duffett CarlsonDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Brendan J CulletonInstitutes of Energy and the Environment, The Pennsylvania State University, University Park, PA, USA.
Laurie EcclesDepartment of Anthropology, Pennsylvania State University, University Park, PA, USA.
Suzanne FreilichDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Denise KeatingDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Ann Marie LawsonDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Kirsten MandlDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Megan MichelDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Jonas OppenheimerDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Kadir Toykan ÖzdoğanDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Kristin StewardsonDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Shaoqing WenInstitute of Archaeological Science, Fudan University, Shanghai, China.
Shi YanSchool of Ethnology and Sociology, Minzu University of China, Beijing, China.ORCID http://orcid.org/0000-0001-8304-8445
Fatma ZalzalaDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Richard ChuangInstitute of Archaeology, National Cheng Kung University, Tainan, Taiwan.
Ching-Jung HuangInstitute of Archaeology, National Cheng Kung University, Tainan, Taiwan.
Hana LoohInstitute of History and Philology, Institute of History and Philology, Academia Sinica, Taipei, Taiwan.
Chung-Ching ShiungInstitute of Archaeology, National Cheng Kung University, Tainan, Taiwan.
Yuri G NikitinMuseum of Archaeology and Ethnology, Institute of History, Archaeology and Ethnology, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia.
Andrei V TabarevInstitute of Archaeology and Ethnography, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
Alexey A TishkinDepartment of Archeology, Ethnography and Museology, Altai State University, Barnaul, Russia.
Song LinKey Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Zhou-Yong SunShaanxi Provincial Institute of Archaeology, Xi'an, China.
Xiao-Ming WuKey Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.ORCID http://orcid.org/0000-0003-0908-0986
Tie-Lin YangKey Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Xi HuKey Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Liang ChenSchool of Cultural Heritage, Northwest University, Xi'an, China.
Hua DuXi'an AMS Center, Institute of Earth Environment, Chinese Academy of Sciences, Xi'an, China.
Jamsranjav BayarsaikhanResearch Center at the National Museum of Mongolia, Ulaanbaatar, Mongolia.
Enkhbayar MijiddorjDepartment of Archaeology, Ulaanbaatar State University, Ulaanbaatar, Mongolia.
Diimaajav ErdenebaatarDepartment of Archaeology, Ulaanbaatar State University, Ulaanbaatar, Mongolia.
Tumur-Ochir IderkhangaiDepartment of Archaeology, Ulaanbaatar State University, Ulaanbaatar, Mongolia.
Erdene MyagmarDepartment of Anthropology and Archaeology, National University of Mongolia, Ulaanbaatar, Mongolia.ORCID http://orcid.org/0000-0003-0400-1177
Hideaki Kanzawa-KiriyamaDepartment of Anthropology, National Museum of Nature and Science, Tsukuba, Japan.
Masato NishinoArchaeological Center of Chiba City, Chiba, Japan.
Ken-Ichi ShinodaDepartment of Anthropology, National Museum of Nature and Science, Tsukuba, Japan.
Olga A ShubinaDepartment of Archeology, Sakhalin Regional Museum, Yuzhno-Sakhalinsk, Russia.
Jianxin GuoDepartment of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Wangwei CaiDepartment of Biochemistry and Molecular Biology, Hainan Medical University, Haikou, China.
Qiongying DengDepartment of Human Anatomy and Center for Genomics and Personalized Medicine, Guangxi Medical University, Nanning, China.
Longli KangKey Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region, Ministry of Education, School of Medicine, Xizang Minzu University (Tibet University for Nationalities), Xianyang, China.
Dawei LiInstitute for History and Culture of Science & Technology, Guangxi University for Nationalities, Nanning, China.
Dongna LiDepartment of Biology, Hainan Medical University, Haikou, China.
Rong LinDepartment of Biology, Hainan Medical University, Haikou, China.ORCID http://orcid.org/0000-0001-9161-6844
NiniKey Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region, Ministry of Education, School of Medicine, Xizang Minzu University (Tibet University for Nationalities), Xianyang, China.
Rukesh ShresthaMOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China.
Ling-Xiang WangMOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China.
Lanhai WeiDepartment of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.ORCID http://orcid.org/0000-0003-3119-7400
Guangmao XieCollege of History, Culture and Tourism, Guangxi Normal University, Guilin, China.
Hongbing YaoBelt and Road Research Center for Forensic Molecular Anthropology, Key Laboratory of Evidence Science of Gansu Province, Gansu Institute of Political Science and Law, Lanzhou, China.
Manfei ZhangMOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China.
Guanglin HeDepartment of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Xiaomin YangDepartment of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Rong HuDepartment of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
Martine RobbeetsEurasia3angle Research group, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0002-2860-0230
Stephan SchiffelsDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0002-1017-9150
Douglas J KennettDepartment of Anthropology, University of California Santa Barbara, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0001-6144-7365
Li JinMOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China.
Hui LiMOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China.
Johannes KrauseDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany. krause@shh.mpg.de.ORCID http://orcid.org/0000-0001-9144-3920
Ron PinhasiDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria. ron.pinhasi@univie.ac.at.ORCID http://orcid.org/0000-0003-1629-8131
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA, USA. reich@genetics.med.harvard.edu.ORCID http://orcid.org/0000-0002-7037-5292
Howard Hughes Medical Institute · USUniversity of Vienna · ATFudan University · CNHarvard University · USXi'an Jiaotong University · CNXiamen University · CNMax Planck Institute for the Science of Human History · DENational Cheng Kung University · TWBroad Institute · USGuangxi University for Nationalities · CNHainan Medical University · CNNational Museum of Nature and Science · JPNational University of Mongolia · MNPennsylvania State University · USXizang Minzu University · CNAltai State University · RUChiba Prefectural Center Museum Otone Branch · JPChinese Academy of Sciences · CNFar Eastern Federal University · RUGansu Institute of Political Science and Law · CN

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
European Research CouncilNIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

The deep population history of East Asia remains poorly understood owing to a lack of ancient DNA data and sparse sampling of present-day people

Indexed as

GenomicsChinaCrop ProductionFemaleGenome, HumanHaplotypesHistory, AncientHuman MigrationHumansJapanLanguageMaleMongoliaNepalOryzaPolymorphism, Single Nucleotide

Identifiers

PMID33618348
PMCPMC7993749
OpenAlexW3129555148

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.