Evidence map›Paper›PMID 33617896›Full record

ReviewProgress in cardiovascular diseases

Asymptomatic peripheral artery disease: Silent but deadly.

Adam A Behroozian, Joshua A Beckman

Open access · greenAbstract readReview
In one paragraph

Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Pulse of Progress: James S.T. Yao, MD, PhD's Breakthrough Ankle-Brachial Index and Biography.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam A BehroozianCardiovascular Division, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua A BeckmanCardiovascular Division, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: Joshua.a.beckman@vumc.org.
Vanderbilt University Medical Center · US

Funding

The Impact of Diabetes on Revascularization in BEST-CLIR01HL131977 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ADAY, AARON W., BECKMAN, JOSHUA A · 2016 to 2020
$4.0M
NHLBI NIH HHS R01 HL131977
6 · The paper itself

Abstract

Peripheral Artery Disease (PAD) is a manifestation of atherosclerosis characterized by diminished perfusion of the limb and a state of dysmetabolism. The asymptomatic PAD phenotype is a relatively recent classification. It is unknown how many people currently live with asymptomatic PAD because there are no universal screening recommendations for patients at risk for PAD. Patients with asymptomatic PAD suffer from a similar risk profile of morbidity and mortality as their counterparts with claudication. Despite this increased risk, there is a dearth of clinical investigations into therapies that specifically benefit the asymptomatic PAD population. At present, current pharmacotherapies that have been studied in PAD patient populations do not stratify by symptom status. We believe that further investigation of the impact of existing therapies in this unique population presents an opportunity to reduce morbidity and mortality due to PAD. This can only be achieved in combination with wide-spread adoption of screening for asymptomatic PAD.

Indexed as

Risk Reduction BehaviorAngiotensin-Converting Enzyme InhibitorsAnkle Brachial IndexAsymptomatic DiseasesCost-Benefit AnalysisDiagnostic Screening ProgramsDiet, HealthyDisease ProgressionExerciseHealth Care CostsHumansHypolipidemic AgentsPeripheral Arterial DiseasePlatelet Aggregation InhibitorsPredictive Value of TestsSmoking CessationAngiotensin-Converting Enzyme InhibitorsHypolipidemic AgentsPlatelet Aggregation InhibitorsAsymptomatic peripheral artery diseaseClaudication

Identifiers

PMID33617896
PMCPMC11824944
OpenAlexW3131240095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.