Evidence map›Paper›PMID 33617875›Full record

ArticleThe Journal of biological chemistry

AKAP79/150 coordinates leptin-induced PKA signaling to regulate K

Veronica A Cochrane, Zhongying Yang, Mark L Dell'Acqua, Show-Ling Shyng

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Subcellular trafficking and endocytic recycling of KAmerican journal of physiology. Cell physiology · 2022
    Review
  9. The Glucagon-Like Adipokinetic Hormone inFrontiers in physiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Veronica A CochraneDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA. Electronic address: cochranv@ohsu.edu.
Zhongying YangDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA.
Mark L Dell'AcquaDepartment of Pharmacology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Show-Ling ShyngDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, USA. Electronic address: shyngs@ohsu.edu.
Oregon Health & Science University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Regulation of Calcium-permeable AMPA Receptors by AKAP79 Postsynaptic SignalingR01NS040701 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DELL'ACQUA, MARK L · 2001 to 2023
$7.7M
KATP channels and insulin secretionR01DK057699 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHYNG, SHOW-LING · 2001 to 2019
$6.1M
Regulation of AKAP79 Postsynaptic Targeting and SignalingR56NS040701 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DELL'ACQUA, MARK L · 2013 to 2013
$540k
NIDDK NIH HHS R01 DK057699NINDS NIH HHS R01 NS040701NINDS NIH HHS R56 NS040701
6 · The paper itself

Abstract

The adipocyte hormone leptin regulates glucose homeostasis both centrally and peripherally. A key peripheral target is the pancreatic β-cell, which secretes insulin upon glucose stimulation. Leptin is known to suppress glucose-stimulated insulin secretion by promoting trafficking of K

Indexed as

Adenosine TriphosphateA Kinase Anchor ProteinsAMP-Activated Protein KinasesCalcineurinCalcium-Calmodulin-Dependent Protein Kinase KinaseCell LineCell MembraneCyclic AMP-Dependent Protein KinasesFluorescence Resonance Energy TransferGlucoseHomeostasisHumansInsulinInsulin-Secreting CellsInsulin SecretionKATP ChannelsAdenosine TriphosphateAKAP5 protein, humanA Kinase Anchor ProteinsAMP-Activated Protein KinasesCalcineurinCalcium-Calmodulin-Dependent Protein Kinase KinaseCyclic AMP-Dependent Protein KinasesGlucoseInsulinKATP ChannelsLeptinA-kinase anchoring protein (AKAP)ATP-sensitive potassium channelcyclic AMP (cAMP)fluorescence resonance energy transfer (FRET)leptinprotein kinase A (PKA)

Identifiers

PMID33617875
PMCPMC8010710
OpenAlexW3133224977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.