Evidence map›Paper›PMID 33617770›Full record

ArticleLancet (London, England)2021

Call to action: how can the US Ending the HIV Epidemic initiative succeed?

Chris Beyrer, Adaora A Adimora, Sally L Hodder, Ernest Hopkins, Greg Millett, Sandra Hsu Hnin Mon, Patrick S Sullivan, Rochelle P Walensky, Anton Pozniak, Mitchell Warren and 3 more

Open access · greenAbstract read
In one paragraph

Article in Lancet (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
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  12. Proposed approaches for public health surveillance: A literature review for the Canadian National HIV Surveillance Program.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  13. Article
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  15. The Future of HIV: Challenges in meeting the 2030medRxiv : the preprint server for health sciences · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Chris BeyrerCenter for Public Health and Human Rights, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. Electronic address: cbeyrer@jhu.edu.
Adaora A AdimoraDepartment of Epidemiology, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC, USA.
Sally L HodderSection of Infectious Diseases, School of Medicine, West Virginia University, Morgantown, WV, USA.
Ernest HopkinsSan Francisco AIDS Foundation, San Francisco, CA, USA.
Greg MillettFoundation for AIDS Research (amfAR), Washington, DC, USA.
Sandra Hsu Hnin MonCenter for Public Health and Human Rights, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Rochelle P WalenskyDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
Anton PozniakDepartment of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK.
Mitchell WarrenAIDS Vaccine Advocacy Coalition (AVAC), New York, NY, USA.
Bruce RichmanPrevention Access Campaign, New York, NY, USA.
Raniyah CopelandBlack AIDS Institute, Los Angeles, CA, USA.
Kenneth H MayerBeth Israel Deaconess Medical Center, Harvard Medical School, Fenway Health, Boston, MA, USA.
Johns Hopkins University · USAIDS Vaccine Advocacy Coalition · USAmerican Foundation for AIDS Research · USBlack AIDS Institute · USChelsea and Westminster Hospital · GBEmory University · USHarvard University · USMassachusetts General Hospital · USSan Francisco AIDS Foundation · USUniversity of North Carolina at Chapel Hill · USWest Virginia University · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
NIAID NIH HHS P30 AI060354NIAID NIH HHS P30 AI094189NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

With more than 1·2 million people living with HIV in the USA, a complex epidemic across the large and diverse country, and a fragmented health-care system marked by widening health disparities, the US HIV epidemic requires sustained scientific and public health attention. The epidemic has been stubbornly persistent; high incidence densities have been sustained over decades and the epidemic is increasingly concentrated among racial, ethnic, and sexual and gender minority communities. This fact remains true despite extraordinary scientific advances in prevention, treatment, and care-advances that have been led, to a substantial degree, by US-supported science and researchers. In this watershed year of 2021 and in the face of the COVID-19 pandemic, it is clear that the USA will not meet the stated goals of the National HIV/AIDS Strategy, particularly those goals relating to reductions in new infections, decreases in morbidity, and reductions in HIV stigma. The six papers in the Lancet Series on HIV in the USA have each examined the underlying causes of these challenges and laid out paths forward for an invigorated, sustained, and more equitable response to the US HIV epidemic than has been seen to date. The sciences of HIV surveillance, prevention, treatment, and implementation all suggest that the visionary goals of the Ending the HIV Epidemic initiative in the USA might be achievable. However, fundamental barriers and challenges need to be addressed and the research effort sustained if we are to succeed.

Indexed as

Public Health AdministrationEpidemicsEpidemiological MonitoringEthnicityHealth Plan ImplementationHealth Status DisparitiesHIV InfectionsHumansMinority GroupsRacial GroupsSexual and Gender MinoritiesSocial Stigma

Identifiers

PMID33617770
PMCPMC8522063
OpenAlexW3130584750

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.