Evidence map›Paper›PMID 33617505›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Longitudinal Symptom Burden Trajectories in a Population-Based Cohort of Women with Metastatic Breast Cancer: A Group-Based Trajectory Modeling Analysis.

Suman Budhwani, Rahim Moineddin, Walter P Wodchis, Camilla Zimmermann, Doris Howell

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Randomized Controlled Trial of Acceptance and Commitment Therapy for Fatigue Interference With Functioning in Metastatic Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Trial
  2. Identifying the trajectory of SPPADE symptoms in patients with cancer using electronic health record data.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. The sharks are circling: a qualitative study of living with metastatic breast cancer.Journal of cancer survivorship : research and practice · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Suman BudhwaniInstitute for Health System Solutions and Virtual Care, Women's College Hospital, Toronto, ON M5S 1B2, Canada.ORCID 0000-0002-6043-149X
Rahim MoineddinDepartment of Family and Community Medicine, University of Toronto, Toronto, ON M5G 1V7, Canada.ORCID 0000-0002-5506-084X
Walter P WodchisInstitute of Clinical Evaluative Sciences, Toronto, ON M4N 3M5, Canada.ORCID 0000-0003-2494-7031
Camilla ZimmermannPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.ORCID 0000-0003-4889-0244
Doris HowellPrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.
University Health Network · CAUniversity of Toronto · CAWomen's College Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the symptom burden trajectory for metastatic breast cancer patients can enable the provision of appropriate supportive care for symptom management. The aim of this study was to describe the longitudinal trajectories of symptom burden for metastatic breast cancer patients at the population-level. A cohort of 995 metastatic breast cancer patients with 16,146 Edmonton Symptom Assessment System (ESAS) assessments was constructed using linked population-level health administrative databases. The patient-reported ESAS total symptom distress score (TSDS) was studied over time using group-based trajectory modeling, and covariate influences on trajectory patterns were examined. Cohort patients experienced symptom burden that could be divided into six distinct trajectories. Patients experiencing a higher baseline TSDS were likely to be classified into trajectory groups with high, uncontrolled TSDS within the study follow-up period (χ

Indexed as

Breast NeoplasmsCohort StudiesDatabases, FactualFemaleHumansPalliative Carebreast neoplasmscohort studieslatent class analysislongitudinal studiesneoplasm metastasispalliative caresymptom assessmentsyndrome

Identifiers

PMID33617505
PMCPMC7985757
OpenAlexW3132198475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.