ArticleCirculation2021
Bending the Curve in Cardiovascular Disease Mortality: Bethesda + 40 and Beyond.
Article in Circulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Physical Activity Levels and Screen Time among Youth with Overweight/Obesity Using Mental Health Services.International journal of environmental research and public health · 2022Trial
- Sustainable and effective lipid-lowering management: prevention strategies from the BRING-UP prevention study.European heart journal. Quality of care & clinical outcomes · 2026Observational
- Prediction of cardiovascular mortality based on iron metabolism in patients with cardiovascular-kidney-metabolic syndrome: development and validation of clinical predictive model.European journal of medical research · 2026Article
- Associated factors of osteoporosis and the impact of osteoporosis on all-cause mortality in incident hemodialysis older patients.Kidney research and clinical practice · 2026Article
- Article
- Emerging role of the cGAS-STING pathway in cardiovascular diseases: biologic function, mechanisms and targeted therapy.Molecular medicine (Cambridge, Mass.) · 2025Review
- Demographic Differences in Mortality in the District of ColumbiaJAMA network open · 2025Article
- Nitric Oxide in Biomaterial-Based Therapies for Coronary Heart Disease: Mechanistic Insights, Current Advances, and Translational Prospects.Biomaterials research · 2025Review
- Causal relationships between serum metabolites and coronary heart disease risk: a mendelian randomization study.Frontiers in genetics · 2025Article
- A Comprehensive Review of Emerging Therapies for Type 2 Diabetes and Their Cardiovascular Effects.Cureus · 2024Review
- An Age-Period-Cohort Analysis of Cardiovascular Disease Mortality in the United States from 1999 to 2018.The American journal of medicine · 2024Article
- Implementing an evidence-based behavioral weight-loss program in community mental health centers: A randomized pilot study.Obesity science & practice · 2024Article
- Finding Optimal Locations for Implementing Innovative Hypertension Management Approaches Among African American Populations: Mapping Barbershops, Hair Salons, and Community Health Centers.Preventing chronic disease · 2024Article
- World Heart Federation Roadmap for Secondary Prevention of Cardiovascular Disease: 2023 Update.Global heart · 2024Article
- US County-Level Variation in Preterm Birth Rates, 2007-2019.JAMA network open · 2023Article
- Association of Population Well-Being With Cardiovascular Outcomes.JAMA network open · 2023Article
- Causes of Death Following Gastric Cancer Diagnosis: A Population-Based Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Comparing Implementation Strategies for an Evidence-Based Weight Management Program Delivered in Community Mental Health Programs: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2023Article
- Projections of future coronary heart disease and stroke mortality in Japan until 2040: a Bayesian age-period-cohort analysis.The Lancet regional health. Western Pacific · 2023Article
- Importance of Optimizing Cardiorespiratory Fitness in Early Adulthood and Through Midlife.JAMA network open · 2023Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
More than 40 years after the 1978 Bethesda Conference on the Declining Mortality from Coronary Heart Disease provided the scientific community with a blueprint for systematic analysis to understand declining rates of coronary heart disease, there are indications the decline has ended or even reversed despite advances in our knowledge about the condition and treatment. Recent data show a more complex situation, with mortality rates for overall cardiovascular disease, including coronary heart disease and stroke, decelerating, whereas those for heart failure are increasing. To mark the 40th anniversary of the Bethesda Conference, the National Heart, Lung, and Blood Institute and the American Heart Association cosponsored the "Bending the Curve in Cardiovascular Disease Mortality: Bethesda + 40" symposium. The objective was to examine the immediate and long-term outcomes of the 1978 conference and understand the current environment. Symposium themes included trends and future projections in cardiovascular disease (in the United States and internationally), the evolving obesity and diabetes epidemics, and harnessing emerging and innovative opportunities to preserve and promote cardiovascular health and prevent cardiovascular disease. In addition, participant-led discussion explored the challenges and barriers in promoting cardiovascular health across the lifespan and established a potential framework for observational research and interventions that would begin in early childhood (or ideally in utero). This report summarizes the relevant research, policy, and practice opportunities discussed at the symposium.
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Registered trials
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