Evidence map›Paper›PMID 33617087›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2021

Minimal clinically important differences in SF-36 global score: Current value in orthopedic oncology.

Koichi Ogura, Meredith K Bartelstein, Mohamed A Yakoub, Zarko Nikolic, Patrick J Boland, John H Healey

Registry-linked trialAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06295276 (Does a Teletherapy-guided Exercise Programme Improve Pain Intensity, Disability, and Quality of Life in Nursing Students With Back and Neck Pain Compared to a Control Group?), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06295276 nacompletednot on this mapstarted 2024, after this paper: background citation

Does a Teletherapy-guided Exercise Programme Improve Pain Intensity, Disability, and Quality of Life in Nursing Students With Back and Neck Pain Compared to a Control Group?

TypeinterventionalSponsorHochschule OsnabruckRan2024 to 2024Enrolled48ConditionsLow Back Pain, Neck PainArmsteletherapy-guided exercise programme, Waiting list/control intervention/delayed teletherapy intervention
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Twenty-five years of experience with patient-reported outcome measures in soft-tissue sarcoma patients: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  3. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Koichi OguraDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Meredith K BartelsteinDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Mohamed A YakoubDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Zarko NikolicDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Patrick J BolandDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
John H HealeyDepartment of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-0802-1186

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The SF-36 is widely used to evaluate the health-related quality of life (HRQoL) of patients with musculoskeletal tumors. Instead of typical methods, calculating the SF-36 Global Score has recently become an increasingly common reporting approach. However, numerical changes lack clear clinical relevance. The minimal clinically important difference (MCID) is useful for interpreting changes in functional scores by defining the smallest change patients may perceive as clinically meaningful. The aim of this study is to determine the MCID of the SF-36 Global Score in orthopedic oncology patients, which has not been reported to date. Three-hundred ten patients who underwent surgery and completed two surveys during postoperative follow-up were reviewed. The two most common methods for calculating the SF-36 Global Score were used: (1) anchor-based methods and receiver operating characteristic analysis based on one-half of the SD of change score and standard error of measurement at baseline and; (2) distribution-based methods. Using anchor-based methods, the MCIDs of SF-36 Global Scores #1 and #2 were 2.7 (area under the curve [AUC] = 0.85) and 2.5 (AUC = 0.79) for improvement, and -1.5 (AUC = 0.81) and -0.6 (AUC = 0.83) for deterioration, respectively. Using distribution-based methods, the MCIDs of SF-36 Global Scores #1 and #2 were 4.1 and 4.4 by half SD, and 4.1 and 4.5 by standard error of measurement, respectively. Our findings provide benchmark values, which can serve as a reference for future studies in musculoskeletal tumor patients using the SF-36 Global Score as a single measure for HRQoL.

Indexed as

NeoplasmsOrthopedicsHumansMinimal Clinically Important DifferenceQuality of LifeSurveys and QuestionnairesTreatment Outcomeanchor-based methoddistribution-based methodhealth-related quality of life (HRQoL)minimal clinically important difference (MCID)sarcomaSF-36 Global Score

Identifiers

PMID33617087
PMCPMC9348556

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.