Evidence map›Paper›PMID 33616792›Full record

ReviewCell and tissue banking2022

Adipose tissue-derived stem cells: a comparative review on isolation, culture, and differentiation methods.

Saber Khazaei, Ghazal Keshavarz, Azam Bozorgi, Hamed Nazari, Mozafar Khazaei

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Cell and tissue banking, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
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  15. Research progress and challenges of stem cell therapy for ischemic stroke.Frontiers in cell and developmental biology · 2024
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Saber KhazaeiDepartment of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID http://orcid.org/0000-0002-9085-1292
Ghazal KeshavarzFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID http://orcid.org/0000-0003-2747-1796
Azam BozorgiFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID http://orcid.org/0000-0002-6863-4611
Hamed NazariDepartment of Orofacial Surgery, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mozafar KhazaeiFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. mkhazaei1345@yahoo.com.ORCID http://orcid.org/0000-0003-0536-3217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue-derived stem cells (ADSCs) are an available source of mesenchymal stem cells with the appropriate capacity to in vitro survive, propagate, and differentiate into cells from three lineages of ectoderm, mesoderm, and endoderm. The biological features of ADSCs depend on the donor physiology and health status, isolation procedure, culture conditions, and differentiation protocols used. Adipose tissue samples are provided by surgery and lipoaspiration-based methods and subjected to various mechanical and chemical digestion techniques to finally generate a heterogeneous mixture named stromal vascular fraction (SVF). ADSCs are purified through varied cell populations that exist within SVF and cultured under standard conditions to give rise to a highly rich resource of stem cells directly applied in the clinic or differentiated into a wide range of cells. The development and optimization of conventional isolation, expansion, and differentiation methods seem noteworthy to preserve the desirable biological functions of ADSCs in pre-clinical and clinical investigations.

Indexed as

Adipose TissueMesenchymal Stem CellsCell DifferentiationCells, CulturedStem CellsAdipose tissue-derived stem cellsCulture conditionsDifferentiation protocolsIsolation procedureStromal vascular fraction

Identifiers

PMID33616792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.