Evidence map›Paper›PMID 33616686›Full record

ReviewAnalytical and bioanalytical chemistry2022

The role of the surface ligand on the performance of electrochemical SARS-CoV-2 antigen biosensors.

Sabine Szunerits, Quentin Pagneux, Abir Swaidan, Vladyslav Mishyn, Alain Roussel, Christian Cambillau, David Devos, Ilka Engelmann, Enagnon Kazali Alidjinou, Henri Happy and 1 more

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. A concise overview of advancements in ultrasensitive biosensor development.Frontiers in bioengineering and biotechnology · 2023
    Review
  5. Nanomaterials-based sensors for the detection of COVID-19: A review.Bioengineering & translational medicine · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19.Frontiers in bioengineering and biotechnology · 2022
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sabine SzuneritsUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France. sabine.szunerits@univ.lille.fr.
Quentin PagneuxUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Abir SwaidanUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Vladyslav MishynUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Alain RousselArchitecture et Fonction des Macromolécules Biologiques, Aix-Marseille Université, Campus de Luminy, CEDEX 20, 13020, Marseille, France.
Christian CambillauArchitecture et Fonction des Macromolécules Biologiques, Aix-Marseille Université, Campus de Luminy, CEDEX 20, 13020, Marseille, France.
David DevosUniv. Lille, CHU-Lille, Inserm, U1172, Lille Neuroscience & Cognition, LICEND, 59000, Lille, France.
Ilka EngelmannUniv. Lille, CHU Lille, Laboratoire de Virologie ULR3610, 59000, Lille, France.
Enagnon Kazali AlidjinouUniv. Lille, CHU Lille, Laboratoire de Virologie ULR3610, 59000, Lille, France.
Henri HappyUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Rabah BoukherroubUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.

Funding

ANR Cordial-FLUI-SITE Unvi. Lille Covid task force
6 · The paper itself

Abstract

Point-of-care (POC) technologies and testing programs hold great potential to significantly improve diagnosis and disease surveillance. POC tests have the intrinsic advantage of being able to be performed near the patient or treatment facility, owing to their portable character. With rapid results often in minutes, these diagnostic platforms have a high positive impact on disease management. POC tests are, in addition, advantageous in situations of a shortage of skilled personnel and restricted availability of laboratory-based analytics. While POC testing programs are widely considered in addressing health care challenges in low-income health systems, the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections could largely benefit from fast, efficient, accurate, and cost-effective point-of-care testing (POCT) devices for limiting COVID-19 spreading. The unrestrained availability of SARS-CoV-2 POC tests is indeed one of the adequate means of better managing the COVID-19 outbreak. A large number of novel and innovative solutions to address this medical need have emerged over the last months. Here, we critically elaborate the role of the surface ligands in the design of biosensors to cope with the current viral outbreak situation. Their notable effect on electrical and electrochemical sensors' design will be discussed in some given examples. Graphical abstract.

Indexed as

Antigens, ViralBiosensing TechniquesCOVID-19COVID-19 TestingElectrochemical TechniquesHumansLigandsPoint-of-Care SystemsPoint-of-Care TestingSARS-CoV-2Antigens, ViralLigandsBiosensorsElectrochemistryField effect transistorsPoint-of-care (POC) technologiesSARS-CoV-2Surface ligands

Identifiers

PMID33616686
PMCPMC7897554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.