ArticleeLife2021
Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Short-Term Axial Length Effects of Combining Paracentral Collimating Apertures with Near-Peripheral Myopic Defocus for Myopia Control.Journal of clinical medicine · 2026Article
- Effect of Chromatic Aberration on White-Light Contrast Sensitivity With Higher-Order Monochromatic Aberrations Correction in the Human Eye in Screen-Based Vision.Translational vision science & technology · 2026Article
- Restoring Vision with Noninvasive Brain Stimulation: A Narrative Review.Ophthalmology and therapy · 2025Review
- Dynamic neural compensation for distorted orientation perception in chronic astigmatism.iScience · 2025Article
- Neural contrast sensitivity is not affected by myopic blur.Scientific reports · 2025Article
- Comparison of Unaided and Aided Visual Acuity in Adults With Down Syndrome.Translational vision science & technology · 2025Article
- Non-orthogonal spectacle correction for irregular astigmatism.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Effects of long-term neural adaptation to habitual sspherical aberration on through-focus visual acuity in adults.Scientific reports · 2024Article
- Comparison of the quantitative contrast sensitivity function between early keratoconus and normal eyes.BMC ophthalmology · 2024Article
- Neural adaptation to the eye's optics through phase compensation.bioRxiv : the preprint server for biology · 2024Article
- Effects of Neural Adaptation to Habitual Spherical Aberration on Depth of Focus.Research square · 2024Article
- Adaptive optics visual simulators: a review of recent optical designs and applications [Invited].Biomedical optics express · 2022Review
- Suprathreshold Contrast Perception Is Altered by Long-term Adaptation to Habitual Optical Blur.Investigative ophthalmology & visual science · 2022Article
- Improvement of neural contrast sensitivity after long-term adaptation in pseudophakic eyes.Biomedical optics express · 2022Article
- Effect of Spectacle Lenses with Highly Aspherical Lenslets on Binocular Vision and Accommodation in Myopic Children with and without Intermittent Exotropia.Journal of ophthalmology · 2022Article
- Assessing the contrast sensitivity function in myopic parafovea: A quick contrast sensitivity functions study.Frontiers in neuroscience · 2022Article
- Article
- Personalized Rehabilitation for Residual Deficits: Tailoring Perceptual Learning for Improved Visual Function in Meridional Amblyopia.Ophthalmology scienceArticle
- Level up the brain! Novel PCA method reveals key neuroplastic refinements in action video gamers.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The eye's optics are a major determinant of visual perception. Elucidating how long-term exposure to optical defects affects visual processing is key to understanding the capacity for, and limits of, sensory plasticity. Here, we show evidence of functional reallocation of sensory processing resources following long-term exposure to poor optical quality. Using adaptive optics to bypass all optical defects, we assessed visual processing in neurotypically-developed adults with healthy eyes and with keratoconus - a corneal disease causing severe optical aberrations. Under fully-corrected optical conditions, keratoconus patients showed altered contrast sensitivity, with impaired sensitivity for fine spatial details and better-than-typical sensitivity for coarse spatial details. Both gains and losses in sensitivity were more pronounced in patients experiencing poorer optical quality in their daily life and mediated by changes in signal enhancement mechanisms. These findings show that adult neural processing adapts to better match the changes in sensory inputs caused by long-term exposure to altered optics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.