Evidence map›Paper›PMID 33615851›Full record

ArticleJournal of diabetes science and technology2022

Tissue Oxygenation Measurements to Aid Scalpel Debridement Removal in Patients With Diabetes.

Kacie Kaile, Jagadeesh Mahadevan, Kevin Leiva, Dinesh Khandavilli, Sivakumar Narayanan, Varalakshmi Muthukrishnan, Wensong Wu, Viswanathan Mohan, Anuradha Godavarty

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kacie KaileOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Jagadeesh MahadevanOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Kevin LeivaOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Dinesh KhandavilliOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.
Sivakumar NarayananDr. Mohan's Diabetes Specialties Centre, Chennai, India.
Varalakshmi MuthukrishnanDr. Mohan's Diabetes Specialties Centre, Chennai, India.
Wensong WuDepartment of Mathematics and Statistics, Florida International University, Miami, FL, USA.
Viswanathan MohanDr. Mohan's Diabetes Specialties Centre, Chennai, India.ORCID 0000-0001-5038-6210
Anuradha GodavartyOptical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA.ORCID 0000-0002-6094-5909
Florida International University · USDr. Mohan's Diabetes Specialities Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCallus formation in the diabetic foot increases the risk of ulcer onset. It is standard procedure to remove these dead tissue layers to reduce rising pressures. In a surgical procedure known as scalpel debridement, or chiropody the callus tissue is removed up to the epidermal layer. Factors may influence the outcome of this surgical process such as clinician inexperience. In an effort to standardize the debridement process, tissue oxygenation (TO) measurements are obtained before and after to study the effect of debridement on callus tissue.

methodsFifteen debridement cases were analyzed using near infrared (NIR) imaging to study changes in TO. The NIR-based device used in this study estimates effective changes in TO in terms of oxy-, deoxy-, total hemoglobin, and oxygen saturation. Weber contrasts between callus tissue and the surrounding normal tissue were compared following debridement for all TO parameters. In a secondary analysis, callus tissue was segmented into quadrants and a percent of significance (in terms of total TO change) was calculated using a

resultsResults show majority of cases displayed greater than 80% as the significant change in TO following debridement, except in cases with the presence of blood clot (a common precursor for ulceration). In cases where incomplete debridement was suspected, a significant change in TO was still observed.

conclusionsWith extensive systematic studies in the future, NIR imaging technique to measure changes in TO may be implemented as a low-cost hand-held imaging device useful for objectively assessing the effectiveness of the scalpel debridement process.

Indexed as

CallositiesDiabetes MellitusDiabetic FootDebridementHumansPressurechiropodydiabetic foot ulcersnear infrared imagingscalpel debridementtissue oxygenationulcer prevention

Identifiers

PMID33615851
PMCPMC8861797
OpenAlexW3132356107

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.