Evidence map›Paper›PMID 33615756›Full record

ArticleJournal of Zhejiang University. Science. B2021

Gastrointestinal toxicities associated with immune checkpoint inhibitors: a disproportionality analysis leveraging VigiBase, the WHO Adverse Drug Reaction Database.

Sifu Huang, Xuefeng Bai, Taiyong Fang, Yanta Guo, Kainan Zheng, Xiahong Lin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Immune checkpoint inhibitor-induced diarrhea and colitis: an overview.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Review
  10. Review
  11. Gastrointestinal perforation associated with novel antineoplastic agents: A real-world study based on the FDA Adverse Event Reporting System.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2023
    Article
  12. Gastrointestinal injury induced by immunomodulators: A review article.Therapeutic advances in gastroenterology · 2023
    Review
  13. Tumor immune checkpoints and their associated inhibitors.Journal of Zhejiang University. Science. B · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sifu HuangDepartment of Gastroenterology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
Xuefeng BaiDepartment of Endocrinology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
Taiyong FangDepartment of Gastroenterology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
Yanta GuoDepartment of Gastroenterology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
Kainan ZhengIT Application Department, Xiamen C&D Corporation Limited, Xiamen 361000, China.
Xiahong LinDepartment of Endocrinology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China. linxiahongdr@fjmu.edu.cn.
Fujian Medical University · CNXiamen Tobacco Industry (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adverse Drug Reaction Reporting SystemsDatabases, FactualGastrointestinal DiseasesHumansImmune Checkpoint InhibitorsImmune Checkpoint Inhibitors

Identifiers

PMID33615756
PMCPMC7885752
OpenAlexW3130837336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.