Evidence map›Paper›PMID 33615534›Full record

ArticleJournal of gastroenterology and hepatology2021

Impact of the coronavirus disease 2019 pandemic on irritable bowel syndrome.

Sabrina Xin Zi Quek, Evelyn Xiu Ling Loo, Alla Demutska, Chun En Chua, Guan Sen Kew, Scott Wong, Hui Xing Lau, En Xian Sarah Low, Tze Liang Loh, Ooi Shien Lung and 18 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  13. Frequency and outcomes of gastrointestinal symptoms in patients with Corona Virus Disease-19.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 14 countries.

Sabrina Xin Zi QuekDepartment of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore.ORCID https://orcid.org/0000-0001-5377-1528
Evelyn Xiu Ling LooDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Alla DemutskaDepartment of Clinical Psychology, James Cook University, Singapore.
Chun En ChuaDepartment of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore.ORCID https://orcid.org/0000-0002-0338-5589
Guan Sen KewDepartment of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore.ORCID https://orcid.org/0000-0002-1918-9857
Scott WongDepartment of Medicine, Ng Teng Fong General Hospital, Singapore.
Hui Xing LauSingapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore.
En Xian Sarah LowDepartment of Medicine, Ng Teng Fong General Hospital, Singapore.ORCID https://orcid.org/0000-0002-8100-9036
Tze Liang LohDepartment of Otorhinolarygology, Head and Neck Surgery, Universiti Putra Malaysia, Seri Kembangan, Malaysia.
Ooi Shien LungDepartment of Anaesthesiology, Columbia Asia Hospital, Miri, Sarawak, Malaysia.
Emily C W HungCambridge Paediatrics, Shatin, Hong Kong.
M Masudur RahmanDepartment of Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0002-9713-2223
Uday C GhoshalDepartment of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Science, Lucknow, India.ORCID https://orcid.org/0000-0003-0221-8495
Sunny H WongDepartment of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID https://orcid.org/0000-0002-3354-9310
Cynthia K Y CheungState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong.
Ari F SyamDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Niandi TanDepartments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-6456-7482
Yinglian XiaoDepartments of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jin-Song LiuDepartment of Gastroenterology, Wuhan Union Hospital of Huazhong University of Science and Technology, Wuhan, Hubei, China.
Fang LuXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Chien-Lin ChenDepartment of Medicine, Buddhist Tzu Chi Hospital and University School of Medicine, Hualien, Taiwan.ORCID https://orcid.org/0000-0002-9084-8210
Yeong Yeh LeeSt George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6486-7717
Ruter M MaralitThe Medical City, Metro Manila, Philippines.
Yong-Sung KimWonkwang Digestive Disease Research Institute, Gut and Food Healthcare, Wonkwang University School of Medicine, Iksan, South Korea.
Tadayuki OshimaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.ORCID https://orcid.org/0000-0001-6949-932X
Hiroto MiwaSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID https://orcid.org/0000-0001-9844-642X
Junxiong PangSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID https://orcid.org/0000-0002-9788-701X
Kewin Tien Ho SiahDepartment of Medicine, Yong Loo Lin School of Medicine, National University Hospital, Singapore.ORCID https://orcid.org/0000-0002-2795-5101
National University of Singapore · SGAgency for Science, Technology and Research · SGChinese University of Hong Kong · HKHanwha Techwin (South Korea) · KRSun Yat-sen University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHyogo Medical University · JPJames Cook University Singapore · SGNational Institute of Neurosciences & Hospital · BDNg Teng Fong General Hospital · SGPharmaceutical Biotechnology (Czechia) · CZPhilippine Medical Association · PHSanjay Gandhi Post Graduate Institute of Medical Sciences · INShatin Hospital · CNSutherland Hospital · AUTzu Chi University · TWUniversiti Putra Malaysia · MYUniversity of Indonesia · IDWonkwang University · KRWuhan Union Hospital · CN

Funding

National University of Singapore IPUR_FY2020_RES_02_PANGNational University of Singapore NUSCOVID19RG-43
6 · The paper itself

Abstract

BACKGROUND AND

aimGastrointestinal manifestations of the coronavirus disease 2019 (COVID-19) pandemic may mimic irritable bowel syndrome (IBS), and social distancing measures may affect IBS patients negatively. We aimed to study the impact of COVID-19 on respondents with self-reported IBS.

methodsWe conducted an anonymized survey from May to June 2020 in 33 countries. Knowledge, attitudes, and practices on personal hygiene and social distancing as well as psychological impact of COVID-19 were assessed. Statistical analysis was performed to determine differences in well-being and compliance to social distancing measures between respondents with and without self-reported IBS. Factors associated with improvement or worsening of IBS symptoms were evaluated.

resultsOut of 2704 respondents, 2024 (74.9%) did not have IBS, 305 (11.3%) had self-reported IBS, and 374 (13.8%) did not know what IBS was. Self-reported IBS respondents reported significantly worse emotional, social, and psychological well-being compared with non-IBS respondents and were less compliant to social distancing measures (28.2% vs 35.3%, P = 0.029); 61.6% reported no change, 26.6% reported improvement, and 11.8% reported worsening IBS symptoms. Higher proportion of respondents with no change in IBS symptoms were willing to practice social distancing indefinitely versus those who deteriorated (74.9% vs 51.4%, P = 0.016). In multivariate analysis, willingness to continue social distancing for another 2-3 weeks (vs longer period) was significantly associated with higher odds of worsening IBS.

conclusionOur study showed that self-reported IBS respondents had worse well-being and compliance to social distancing measures than non-IBS respondents. Future research will focus on occupational stress and dietary changes during COVID-19 that may influence IBS.

Indexed as

PandemicsPatient ComplianceSARS-CoV-2Self ReportAdultCOVID-19Cross-Sectional StudiesFemaleHumansIrritable Bowel SyndromeMaleRetrospective StudiesSingaporeSurveys and QuestionnairesCOVID-19IBSSocial distancing

Identifiers

PMID33615534
PMCPMC8014795
OpenAlexW3129201862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.