Evidence map›Paper›PMID 33615438›Full record

ArticleChild development2021

Declining Gaze to Faces in Infants Developing Autism Spectrum Disorder: Evidence From Two Independent Cohorts.

Devon N Gangi, Sofie Boterberg, Amy J Schwichtenberg, Erika Solis, Gregory S Young, Ana-Maria Iosif, Sally Ozonoff

Abstract read
In one paragraph

Article in Child development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Trajectory research in children with an autism diagnosis: A scoping review.Autism : the international journal of research and practice · 2024
    Article
  5. Article
  6. Infant sleep predicts trajectories of social attention and later autism traits.Journal of child psychology and psychiatry, and allied disciplines · 2023
    Article
  7. Article
  8. Ethical dimensions of translational developmental neuroscience research in autism.Journal of child psychology and psychiatry, and allied disciplines · 2021
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devon N GangiUniversity of California, Davis.ORCID 0000-0003-2885-4641
Sofie BoterbergGhent University.
Amy J SchwichtenbergPurdue University.
Erika SolisUniversity of California, Davis.
Gregory S YoungUniversity of California, Davis.
Ana-Maria IosifUniversity of California, Davis.ORCID 0000-0001-7283-2015
Sally OzonoffUniversity of California, Davis.

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JUDY A. VAN DE WATER · 2020 to 2026
$9.7M
Infants at Risk of Autism: A Longitudinal StudyR01MH068398 · NIMH · UNIVERSITY OF CALIFORNIA DAVIS · PI OZONOFF, SALLY · 2003 to 2013
$6.1M
Development of a Prospective Video-Based Measure to Identify ASD Risk in InfancyR01MH099046 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OZONOFF, SALLY · 2013 to 2016
$2.0M
Autism Speaks AS8370NICHD NIH HHS P50 HD103526NIMH NIH HHS R01 MH068398NIMH NIH HHS R01 MH099046
6 · The paper itself

Abstract

Two independent cohorts (N = 155, N = 126) of infants at high and low risk for autism spectrum disorder (ASD) were followed prospectively between 6 and 36 months of age, when n = 46 were diagnosed with ASD. Gaze to adult faces was coded-during a developmental assessment (Cohort 1) or a play interaction (Cohort 2). Across both cohorts, most children developing ASD showed sharp declines in gaze to faces over time, relative to children without ASD. These findings suggest that declining developmental trajectories may be more common than previously recognized by retrospective methods. Trajectory-based screening methods could potentially identify children in the early stages of symptom onset and allow for early intervention before the full disorder has developed.

Indexed as

Autism Spectrum DisorderCohort StudiesHumansInfantRetrospective StudiesRisk

Identifiers

PMID33615438
PMCPMC8169511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.