ArticleWorld journal of urology2021
The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010-2019.
Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- [Prostate biopsy-infection prophylaxis and patient preparation].Urologie (Heidelberg, Germany) · 2023Pooled it
- Accuracy and safety of in-office transperineal freehand cognitive fusion prostate biopsy under local anaesthesia without antibiotic prophylaxis.Scientific reports · 2025Article
- Reassessing the evidence on transperineal prostate biopsy without antibiotic prophylaxis.World journal of urology · 2025Article
- Use versus nonuse of antimicrobial prophylaxis prior to transperineal prostate biopsy: a propensity score-matched analysis.Prostate international · 2025Article
- An antimicrobial stewardship intervention on antibiotic prophylaxis for transrectal prostate biopsies in a veteran population.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- [Perineal prostate biopsy].Urologie (Heidelberg, Germany) · 2024Review
- Microbiology of infection-related complications after transrectal ultrasound-guided prostate biopsy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Transition from Transrectal to Transperineal MRI-Fusion Prostate Biopsy Does Not Comprise Detection Rates of Clinically Significant Prostate Cancer at a Tertiary Care Center.Diagnostics (Basel, Switzerland) · 2024Article
- Antimicrobial prophylaxis: To do or not to do? This is the question.Prostate cancer and prostatic diseases · 2024Article
- Infectious complications of transrectal prostate biopsy in patients receiving targeted antibiotic prophylaxis after urethral and rectal swab versus standard prophylaxis: A prospective comparative study.Prostate international · 2024Article
- Complication rates of ciprofloxacin alone vs. ciprofloxacin plus fosfomycin for transrectal prostate biopsy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Phytotherapy Might Have a Role in Reducing Unnecessary Prostate Biopsies: Results from an Exploratory, Randomized Controlled Trial of Two Different Phytotherapeutic Agents.Clinics and practice · 2024Article
- Surveillance and Stewardship: Where Infection Prevention and Antimicrobial Stewardship Intersect.Open forum infectious diseases · 2023Article
- Clinical Value of a Routine Urine Culture Prior to Transrectal Prostate Biopsy.European urology open science · 2023Article
- Cost-Effectiveness Analysis of Stockholm 3 Testing Compared to PSA as the Primary Blood Test in the Prostate Cancer Diagnostic Pathway: A Decision Tree Approach.Applied health economics and health policy · 2022Article
- Antibiotic prophylaxis in patients who had undergone to prostate biopsy in between the EMA warning era: effects of fluoroquinolones in diabetic and non-diabetic patients. Results of an observational cohort study.World journal of urology · 2022Observational
Corrections and comments
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Authors and funding
14 authors at 10 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate and report the complications, and to analyse antimicrobial stewardship aspects following prostate biopsies (P-Bx) based on the data from a 9-year global study.
methodsThe primary outcome was to compare complications after P-Bx between patients of two cohorts: 2010-2014 and 2016-2019. Primary outcomes included symptoms of lower and severe/systemic urinary tract infection (LUTIS and SUTIS, respectively), and positive urine culture. Readmission to hospital after P-Bx, need for additional antimicrobial therapy, consumption of different antimicrobial agents for prophylaxis and therapy were evaluated. Students t test and chi-square test were used for comparative analyses.
resultsOutcome data were available for 1615 men. Fluoroquinolones-based prophylaxis rate increased from 72.0% in 2010-2014 to 78.6% in 2015-2019. Overall rates of complications increased from 6 to 11.7% including an increase in symptomatic complications from 4.7 to 10.2%, mainly due to an increase in LUTIS. Rates of patients seeking additional medical help in primary care after P-Bx increased from 7.4 to 14.4%; cases requiring post P-Bx antibiotic treatment increased from 6.1 to 9.7%, most of which received fluoroquinolones. Transperineal P-Bx was significantly associated with LUTIS. Following transrectal P-Bx, 2.8% developed febrile infections and 4.0% required hospitalisation. Two men (0.12%) died after transrectal P-Bx due to sepsis.
conclusionsThe rates of complications after P-Bx tended to increase in time, as well as rates of patients seeking additional medical help in the post-P-Bx period. To reduce the risk of infectious complications and to comply with the principles of antibiotic stewardship, clinicians should switch to the transperineal biopsy route.
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