Evidence map›Paper›PMID 33615264›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2021

Blood Flow Restriction Training Using the Delfi System Is Associated With a Cellular Systemic Response.

Mark C Callanan, Hillary A Plummer, Garrett L Chapman, Tyler J Opitz, Nicole K Rendos, Adam W Anz

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07213726 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Quantification of Peripheral Hematopoietic Progenitor Cell Circulation Following Repeated Acute, Vascular Restriction Resistance Exercise Using the Delfi Tourniquet System

TypeinterventionalSponsorAndrews Research & Education FoundationRan2022 to 2026Enrolled15ConditionsBlood Flow Restriction (BFR) Training EffectsArmsDelfi Personalized Tourniquet System
NCT07498166 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

TypeinterventionalSponsorMassachusetts General HospitalRan2026 to 2027Enrolled75ConditionsAchilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow RestrictionArmsBlood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. The Current Role of Biologics for Meniscus Injury and Treatment.Current reviews in musculoskeletal medicine · 2022
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mark C CallananThe Orthopedic Clinic, Shreveport, Louisiana, U.S.A.
Hillary A PlummerAndrews Research & Education Foundation, Gulf Breeze, Florida, U.S.A.
Garrett L ChapmanBeaver Medical Group, Redlands, California, U.S.A.
Tyler J OpitzAndrews Institute for Orthopedics & Sports Medicine, Gulf Breeze, Florida, U.S.A.
Nicole K RendosAndrews Research & Education Foundation, Gulf Breeze, Florida, U.S.A.
Adam W AnzAndrews Institute for Orthopedics & Sports Medicine, Gulf Breeze, Florida, U.S.A.
Andrews Institute for Orthopaedics & Sports Medicine · USAndrews Research & Education Foundation · USBeaver Medical Group · USLouisiana State University in Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the effects of blood flow restriction (BFR) exercise on CD34

methodsHealthy participants aged 20 to 39 years who were able to perform the exercise sessions were recruited. Participants underwent an experimental (EXP) occluded testing session and a control (CON) session using the Delfi Personalized Tourniquet System. Blood draws were performed prior to testing and immediately after the exercise session. Blood analysis consisted of a complete blood count as well as flow cytometry to measure peripheral CD34

resultsFourteen men (aged 30.8 ± 3.9 years) volunteered. There was a significant increase in average CD34

conclusionsExercise with BFR causes a significant post-exercise increase in peripheral hematopoietic progenitor cells and platelets, beyond that of standard resistance training. CLINICAL RELEVANCE: BFR can be considered a way to manipulate point-of-care blood products such as platelet-rich plasma to increase product yield.

Identifiers

PMID33615264
PMCPMC7879193
OpenAlexW3117126378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.