Evidence map›Paper›PMID 33615087›Full record

ArticleCurrent opinion in physiology2021

Cellular Diversity and Regeneration in Taste Buds.

Thomas E Finger, Linda A Barlow

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. [Chinese Expert Consensus on Delta-like Ligand 3-T Cell Engager Therapy 
for SCLC].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026
    Review
  5. Article
  6. Nerve Injury-Induced Immune Responses in the Taste Bud Target Field.International journal of molecular sciences · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Developing and regenerating a sense of taste.Current topics in developmental biology · 2025
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas E FingerDept. Cell & Developmental Biology, Univ. Colorado School of Medicine, Anschutz Medical Campus, MS 8108, Room L18-11118, RC-1, 12801 E. 17th Ave., Aurora CO 80045.
Linda A BarlowDept. Cell & Developmental Biology, Univ. Colorado School of Medicine, Anschutz Medical Campus, MS 8108, Room L18-11118, RC-1, 12801 E. 17th Ave., Aurora CO 80045.
University of Colorado Anschutz Medical Campus · US

Funding

Mechanisms of Adult Taste Bud RegenerationR01DC012383 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI BARLOW, LINDA A · 2012 to 2021
$3.4M
Characterization of progenitor populations in adult taste epitheliumR01DC018489 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI BARLOW, LINDA A · 2020 to 2024
$2.5M
Illuminating the structure and function of Type I taste cellsR01DC017679 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI KINNAMON, SUE C. · 2019 to 2023
$2.5M
Scanning Blockface EM of Murine and Human Taste BudsR01DC014728 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI FINGER, THOMAS E · 2015 to 2020
$1.9M
Use of lingual organoids to screen for the impact of targeted cancer therapies on taste bud renewalR21CA236480 · NCI · UNIVERSITY OF COLORADO DENVER · PI BARLOW, LINDA A · 2019 to 2020
$372k
NCI NIH HHS R21 CA236480NIDCD NIH HHS R01 DC012383NIDCD NIH HHS R01 DC014728NIDCD NIH HHS R01 DC017679NIDCD NIH HHS R01 DC018489
6 · The paper itself

Abstract

Taste buds are the sensory end organs for gustation, mediating sensations of salty, sour, bitter, sweet and umami as well as other possible modalities, e.g. fat and kokumi. Understanding of the structure and function of these sensory organs has increased greatly in the last decades with advances in ultrastructural methods, molecular genetics, and in vitro models. This review will focus on the cellular constituents of taste buds, and molecular regulation of taste bud cell renewal and differentiation.

Indexed as

adult stem cellsATPLGR5neurotransmitterSonic HedgehogSOX2Taste ReceptorsWNT

Identifiers

PMID33615087
PMCPMC7888981
OpenAlexW3120733626

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.