ArticleLaryngoscope investigative otolaryngology2021
Tinnitus and auditory cortex; Using adapted functional near-infrared-spectroscopy to expand brain imaging in humans.
Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Using ALE coordinate-based meta-analysis to observe resting-state brain abnormalities in subjective tinnitus.Brain imaging and behavior · 2024Pooled it
- Changes in temporal lobe activation during a sound stimulation task in patients with sensorineural tinnitus: a multi-channel near-infrared spectroscopy study.Biomedical engineering online · 2024Article
- Application of functional near-infrared spectroscopy (fNIRS) in tinnitus research: contemporary insights and perspectives.Frontiers in psychology · 2024Article
- Increased pyramidal and VIP neuronal excitability in rat primary auditory cortex directly correlates with tinnitus behaviour.The Journal of physiology · 2023Article
- Differential cortical activation patterns: pioneering sub-classification of tinnitus with and without hyperacusis by combining audiometry, gamma oscillations, and hemodynamics.Frontiers in neuroscience · 2023Article
- Tinnitus and auditory cortex; Using adapted functional near-infrared-spectroscopy to expand brain imaging in humans.Laryngoscope investigative otolaryngology · 2021Article
- The Pathological Mechanisms and Treatments of Tinnitus.Discoveries (Craiova, Romania)Review
- Dynamic changes in brain network functional connectivity following repositioning treatment for benign paroxysmal positional vertigo: an fNIRS study.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
objectivesPhantom sound perception (tinnitus) may arise from altered brain activity within auditory cortex. Auditory cortex neurons in tinnitus animal models show increased spontaneous firing rates. This may be a core characteristic of tinnitus. Functional near-infrared spectroscopy (fNIRS) has shown similar findings in human auditory cortex. Current fNIRS approaches with cap recordings are limited to ∼3 cm depth of signal penetration due to the skull thickness. To address this limitation, we present an innovative fNIRS approach via probes adapted to the external auditory canal. The adapted probes were placed deeper and closer to temporal lobe of the brain to bypass confining skull bone and improve neural recordings.
methodsTwenty adults with tinnitus and 20 nontinnitus controls listened to periods of silence and broadband noise (BBN) during standard cap and adapted ear canal fNIRS neuroimaging. The evaluators were not blinded, but the protocol and postprocessing for the two groups were identical.
resultsStandard fNIRS measurements in participants with tinnitus revealed increased auditory cortex activity during silence that was suppressed during auditory stimulation with BBN. Conversely, controls displayed increased activation with noise but not during silence. Importantly, adapted ear canal fNIRs probes showed similar hemodynamic responses seen with cap probes in both tinnitus and controls.
conclusionsIn this LEVEL OF EVIDENCE: NA.
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