ArticleAlzheimer's & dementia (New York, N. Y.)2021
Association of the use of hearing aids with the conversion from mild cognitive impairment to dementia and progression of dementia: A longitudinal retrospective study.
Article in Alzheimer's & dementia (New York, N. Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Umbrella review and Delphi study on modifiable factors for dementia risk reduction.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Does social isolation mediate the association between hearing loss and cognition in adults? A systematic review and meta-analysis of longitudinal studies.Frontiers in public health · 2024Pooled it
- Trial
- Hearing Intervention for Older Adults With Mild Cognitive Impairment: The CHOICE Randomized Clinical Trial.JAMA neurology · 2026Article
- Hearing Loss and Dementia: Risk Factor, Early Marker, or Both?Healthcare (Basel, Switzerland) · 2026Review
- Association between hearing aid use and cognitive function among Chinese middle-aged and older adults with hearing impairment: the mediating effect of social activity.Journal of global health · 2026Article
- Hearing aid effectiveness and probable dementia risk across 33 countries: A pooled analysis of seven cohorts.Cell reports. Medicine · 2026Article
- Article
- Development and Validation of Machine Learning Models for Predicting Early Cognitive Decline Using Home Sensor-Derived Behavioral Data: Sensors in-Home for Elder Wellbeing (SINEW) Cohort Study.JMIR research protocols · 2026Article
- [Current status and future perspectives on age-related hearing loss and cognitive impairment].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Review
- Evaluating the Impact of Cochlear Implantation on Cognitive Outcomes in Older Adults: A 5-Year Follow-Up.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026Article
- Risk of dementia and related neurocognitive disorders among autistic and non-autistic older adults: role of established risk factors.Age and ageing · 2026Article
- Dementia and hearing loss: from risk to mechanisms and management.Frontiers in dementia · 2026Review
- Cognitive Reserve and Its Relationship With Memory Changes: An Analysis of the Survey of Health, Aging, and Retirement in Europe (SHARE).International journal of geriatric psychiatry · 2026Article
- Hearing technology and the brain: cognitive function in different hearing device users.Frontiers in aging neuroscience · 2026Article
- Cognitive function trajectories and influencing factors in Chinese older adults with self-reported hearing impairment: findings from CHARLS 2013-2020.BMC geriatrics · 2025Article
- A mini review of transforming dementia care in China with data-driven insights: overcoming diagnostic and time-delayed barriers.Frontiers in aging neuroscience · 2025Review
- Hearing Loss, Hearing Aids, and Cognition.JAMA network open · 2024Article
- Effects of cochlear implantation on cognitive decline in older adults: A systematic review and meta-analysis.Heliyon · 2023Article
- Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
introductionHearing aid usage has been linked to improvements in cognition, communication, and socialization, but the extent to which it can affect the incidence and progression of dementia is unknown. Such research is vital given the high prevalence of dementia and hearing impairment in older adults, and the fact that both conditions often coexist. In this study, we examined for the first time the effect of the use of hearing aids on the conversion from mild cognitive impairment (MCI) to dementia and progression of dementia.
methodsWe used a large referral-based cohort of 2114 hearing-impaired patients obtained from the National Alzheimer's Coordinating Center. Survival analyses using multivariable Cox proportional hazards regression model and weighted Cox regression model with censored data were performed to assess the effect of hearing aid use on the risk of conversion from MCI to dementia and risk of death in hearing-impaired participants. Disease progression was assessed with Clinical Dementia Rating Sum of Boxes (CDR-SB) scores. Three types of sensitivity analyses were performed to validate the robustness of the results.
resultsMCI participants that used hearing aids were at significantly lower risk of developing all-cause dementia compared to those not using hearing aids (hazard ratio [HR] 0.73, 95% confidence interval [CI], 0.61 to 0.89; false discovery rate [FDR] DISCUSSION: Among hearing-impaired adults, hearing aid use was independently associated with reduced dementia risk. The causality between hearing aid use and incident dementia should be further tested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.