Evidence map›Paper›PMID 33614873›Full record

ArticleData in brief2021

Impact of 10-valent Pneumococcal Conjugate Vaccine (PCV10) on nasopharyngeal carriage in children 2 years of age: Data from a four-year time series cross-sectional study from Pakistan.

Muhammad Imran Nisar, Shahira Shahid, Sajid Muhammad, Farah Khalid, Amjad Hussain, Sheraz Ahmed, Sadia Shakoor, Furqan Kabir, Aneeta Hotwani, Asad Ali and 4 more

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Muhammad Imran NisarDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Shahira ShahidDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Sajid MuhammadDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Farah KhalidDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Amjad HussainDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Sheraz AhmedDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Sadia ShakoorDepartment of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.
Furqan KabirDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Aneeta HotwaniDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Asad AliDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Anita Km ZaidiDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Saad B OmerYale Institute for Global Health, New Haven, CT, USA.
Fyezah JehanDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Najeeha IqbalDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Aga Khan University · PKBill & Melinda Gates Foundation · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Medical Research Council MR/L004283/1NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The dataset described in this paper was collected for a time-series cross-sectional study exploring the impact of 10-valent Pneumococcal Conjugate Vaccine (PCV10) on nasopharyngeal (NP) carriage in children under 2 years of age from a rural population in Sindh, Pakistan. The study was carried out in two union councils of Matiari - Khyber and Shah Alam Shah Jee Wasi (Latitude 25.680298 / Longitude 68.502711). Data was collected on socio-demographics, clinical characteristics and vaccination status using android phone-based application. NP samples were collected using standard World Health Organisation (WHO) techniques, culture and serotyping was done using sequential Multiplex PCR described by Centre for Disease Control, USA. We looked at the carriage rate of vaccine type (VT) and non-vaccine type (NVT) serotypes over time in vaccinated and unvaccinated children. We additionally looked at the predictors for pneumococcal carriage. The uploaded dataset, available on Mendeley data repository (Nisar, Muhammad Imran (2021), "Impact of PCV10 on nasopharyngeal carriage in children in Pakistan", Mendeley Data, V1, doi:10.17632/t79h6g97gr.1), has 3140 observations in CSV format. Additional files uploaded include a data dictionary and the set of questionnaires. The dataset and accompanying files can be used by other interested researchers to replicate our analysis, carry similar analysis under varying set of assumptions or perform additional exploratory or metanalysis.

Indexed as

Herd ImmunityNasopharyngeal carriagePakistanPneumococcal VaccinesStreptococcus pneumoniaeSurveillance

Identifiers

PMID33614873
PMCPMC7881212
OpenAlexW3126716366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.