Evidence map›Paper›PMID 33614858›Full record

ArticleOptica2019

Measuring and compensating for ocular longitudinal chromatic aberration.

Xiaoyun Jiang, James A Kuchenbecker, Phanith Touch, Ramkumar Sabesan

Abstract read
In one paragraph

Article in Optica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Head-mounted adaptive optics visual simulator.Biomedical optics express · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Effect of cone spectral topography on chromatic detection sensitivity.Journal of the Optical Society of America. A, Optics, image science, and vision · 2020
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyun JiangDepartment of Ophthalmology, University of Washington, Seattle, Washington 98109, USA.
James A KuchenbeckerDepartment of Ophthalmology, University of Washington, Seattle, Washington 98109, USA.
Phanith TouchDepartment of Ophthalmology, University of Washington, Seattle, Washington 98109, USA.
Ramkumar SabesanDepartment of Ophthalmology, University of Washington, Seattle, Washington 98109, USA.

Funding

Vision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI JAMES Bryant HURLEY · 1985 to 2026
$23.5M
Photoreceptor mosaic in health and diseaseR01EY029710 · NEI · UNIVERSITY OF WASHINGTON · PI Ramkumar Sabesan · 2019 to 2026
$2.9M
In vivo photoreceptor physiology in the human retinaR21EY027941 · NEI · UNIVERSITY OF WASHINGTON · PI SABESAN, RAMKUMAR · 2018 to 2019
$432k
NEI NIH HHS P30 EY001730NEI NIH HHS R01 EY029710NEI NIH HHS R21 EY027941
6 · The paper itself

Abstract

It is well known that the eye's optics and media introduce monochromatic and chromatic aberration unique to each individual. Once monochromatic aberrations are removed with adaptive optics (AO), longitudinal chromatic aberrations (LCA) define the fidelity for multi-wavelength, high-resolution vision testing and retinal imaging. AO vision simulation systems and AO scanning laser ophthalmoscopes (AOSLOs) typically use the average population LCA to compensate for focus offsets between different wavelengths precluding fine, individualized control. The eye's LCA has been characterized extensively using either subjective (visual perception) or objective (imaging) methods. Classically, these have faced inconsistencies due to extraneous factors related to depth of focus, monochromatic aberration, and wavelength-dependent light interactions with retinal tissue. Here, we introduce a filter-based Badal LCA compensator that offers the flexibility to tune LCA for each individual eye and demonstrate its feasibility for vision testing and imaging using multiple wavelengths simultaneously. Incorporating the LCA compensator in an AOSLO allowed the first objective measurements of LCA based on confocal, multi-wavelength foveal cone images and its comparison to measures obtained subjectively. The objective LCA thus obtained was consistent with subjective estimates in the same individuals and hence resolves the prior discrepancies between them. Overall, the described approach will benefit applications in retinal imaging and vision testing where the focus of multiple wavelengths needs to be controlled independently and simultaneously.

Identifiers

PMID33614858
PMCPMC7894623

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.