Evidence map›Paper›PMID 33614813›Full record

ArticleOpen forum infectious diseases2021

Jonathan P Huggins, Samuel Hohmann, Michael Z David

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. A Review of Current Insights in Fungal Endocarditis.Journal of clinical medicine · 2025
    Review
  6. IDCases · 2024
    Article
  7. Review
  8. An overview of infective endocarditis in the context of COVID-19 pneumonia.European heart journal. Imaging methods and practice · 2023
    Article
  9. Article
  10. Article
  11. Prosthetic valve endocarditis due toAccess microbiology · 2023
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jonathan P HugginsDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Samuel HohmannDepartment of Health Systems Management, Rush University, Chicago, Illinois, USA.
Michael Z DavidDepartment of Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Duke Medical Center · USHospital of the University of Pennsylvania · USRush University · US

Funding

Infectious Diseases Epidemiology Training GrantT32AI055435 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LAUTENBACH, EBBING · 2003 to 2023
$6.9M
Genomics of S. Aureus Colonization after Initial and Recurrent Skin Infections and the Impact of AntibioticsR01AI139188 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DAVID, MICHAEL ZDENEK · 2018 to 2022
$3.8M
NIAID NIH HHS R01 AI139188NIAID NIH HHS T32 AI055435
6 · The paper itself

Abstract

background

methodsThis was a multicenter, retrospective cohort study of 703 inpatients admitted to 179 US hospitals between October 2015 and April 2019. We reviewed demographic, diagnostic, medication administration, and procedural data from each patient's initial encounter. Univariate and multivariate logistic regression analyses were used to identify predictors of in-hospital mortality.

resultsOf 703 patients, 114 (16.2%) died during the index encounter. One hundred fifty-eight (22.5%) underwent an intervention on a cardiac valve. On multivariate analysis, acute and subacute liver failure was the strongest predictor of death (odds ratio [OR], 9.2; 95% confidence interval [CI], 4.8 -17.7). Female sex (OR, 1.9; 95% CI, 1.2-3.0), transfer from an outside medical facility (OR, 1.8; 95% CI, 1.1-2.8), aortic valve pathology (OR, 2.7; 95% CI, 1.5-4.9), hemodialysis (OR, 2.1; 95% CI, 1.1-4.0), cerebrovascular disease (OR, 2.2; 95% CI, 1.2-3.8), neutropenia (OR, 2.5; 95% CI, 1.3-4.8), and alcohol abuse (OR, 2.9; 95% CI, 1.3-6.7) were also associated with death on adjusted analysis, whereas opiate abuse was associated with a lower odds of death (OR, 0.5; 95% CI, 0.2-0.9).

conclusionsWe found that the inpatient mortality rate was 16.2% among patients with

Indexed as

Candidacandidemiaendocarditis

Identifiers

PMID33614813
PMCPMC7881760
OpenAlexW3114872626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.