Evidence map›Paper›PMID 33614772›Full record

ArticleERJ open research2021

Underestimation of COVID-19 mortality during the pandemic.

Stacey Kung, Marjan Doppen, Melissa Black, Irene Braithwaite, Ciléin Kearns, Mark Weatherall, Richard Beasley, Nethmi Kearns

Abstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stacey KungMedical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0003-0631-1857
Marjan DoppenMedical Research Institute of New Zealand, Wellington, New Zealand.
Melissa BlackMedical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0002-5340-643X
Irene BraithwaiteMedical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0001-5327-3027
Ciléin KearnsMedical Research Institute of New Zealand, Wellington, New Zealand.
Mark WeatherallDept of Medicine, University of Otago, Wellington, New Zealand.
Richard BeasleyMedical Research Institute of New Zealand, Wellington, New Zealand.ORCID https://orcid.org/0000-0003-0337-406X
Nethmi KearnsMedical Research Institute of New Zealand, Wellington, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been considerable international variation in mortality during the COVID-19 pandemic. The objective of this study was to investigate the differences between mortality registered as due to COVID-19 and the excess all-cause mortality reported in countries worldwide during the COVID-19 pandemic.

methodsEcological analysis of 22 countries compared 5-year historical all-cause mortality, reported all-cause mortality and expected all-cause mortality (calculated as historical mortality plus the reported deaths attributed to COVID-19). Data available from the first week of January 2020 to that most recently available were analysed.

resultsCompared to the preceding 5 years, there was an excess of 716 616 deaths, of which 64.3% were attributed to COVID-19. The proportion of deaths registered as COVID-19-related/excess deaths varied markedly between countries, ranging between 30% and 197% in those countries that had an excess of deaths during the period of observation. In most countries where a definite peak in COVID-19-related deaths occurred, the increase in reported all-cause mortality preceded the increase in COVID-19 reported mortality. During the latter period of observation, a few countries reported fewer all-cause deaths than the historical figures.

conclusionThe increases in all-cause mortality preceded the increase in COVID-19 mortality in most countries that had definite spikes in COVID-19 mortality. The number of deaths attributed to COVID-19 was underestimated by at least 35%. Together these findings suggest that calculation of excess all-cause mortality is a better predictor of COVID-19 mortality than the reported rates, in those countries experiencing definite increases in mortality.

Identifiers

PMID33614772
PMCPMC7734715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.