Evidence map›Paper›PMID 33614525›Full record

ArticleFrontiers in cellular and infection microbiology2020

HIV-1 Infection Is Associated With Increased Prevalence and Abundance of

Deborah M Stiffler, Janet Oyieko, Carolyne M Kifude, David M Rockabrand, Shirley Luckhart, V Ann Stewart

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Longitudinal impact of asymptomatic malaria/HIV-1 co-infection onFrontiers in cellular and infection microbiology · 2022
    Article
  5. Article
  6. HIV-1 Impact on Malaria Transmission: A Complex and Relevant Global Health Concern.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Deborah M StifflerDepartment of Preventive Medicine and Biostatistics, Division of Tropical Public Health, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Janet OyiekoBasic Science Laboratory, US Army Medical Research Directorate-Africa/Kenya Medical Research Institute, Kisumu, Kenya.
Carolyne M KifudeBasic Science Laboratory, US Army Medical Research Directorate-Africa/Kenya Medical Research Institute, Kisumu, Kenya.
David M RockabrandDepartment of Preventive Medicine and Biostatistics, Division of Tropical Public Health, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Shirley LuckhartDepartment of Entomology, Plant Pathology and Nematology and Department of Biological Sciences, University of Idaho, Moscow, ID, United States.
V Ann StewartDepartment of Preventive Medicine and Biostatistics, Division of Tropical Public Health, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Uniformed Services University of the Health Sciences · USKenya Medical Research Institute · KEUnited States Army Medical Research Directorate - Africa · KEUniversity of Idaho · US

Funding

The Burden of Malaria Transmission due to Asymptomatic HIV Co-InfectionR01AI104423 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI LUCKHART, SHIRLEY, STEWART, V. ANN · 2012 to 2016
$2.8M
NIAID NIH HHS R01 AI104423
6 · The paper itself

Abstract

As morbidity and mortality due to malaria continue to decline, the identification of individuals with a high likelihood of transmitting malaria is needed to further reduce the prevalence of malaria. In areas of holoendemic malaria transmission, asymptomatically infected adults may be infected with transmissible gametocytes. The impact of HIV-1 on gametocyte carriage is unknown, but co-infection may lead to an increase in gametocytemia. In this study, a panel of qPCR assays was used to quantify gametocyte stage-specific transcripts present in dried blood spots obtained from asymptomatic adults seeking voluntary HIV testing in Kombewa, Kenya. A total of 1,116

Indexed as

HIV-1HIV InfectionsMalaria, FalciparumAdultHumansKenyaMalePlasmodium falciparumPrevalenceasymptomaticco-infectiongametocyteHIVHIV-1malariaPlasmodium falciparumtransmission

Identifiers

PMID33614525
PMCPMC7892447
OpenAlexW3128624741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.